Protein Alignment ey and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_113925.1
• Gene: Nkx6-1 / 65193
• RGDID: 69318
• Length: 365
• Species: Rattus norvegicus
• Alignment Length: 375
• Identity: 91/375 - (24%)
• Similarity: 124/375 - (33%)
• Gaps: 127/375 - (33%)

  Fly   232 TG--SGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATP-------------- 280
            ||  |.|||:|:.:|.|..:.....|.:...|:|...:|.|....:..|||
  Rat    45 TGPPSSSSSSSSSSSPSPPLGAHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPV 109

  Fly   281 -----LNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSS 340
                 |.|:...|:|:|...|....            :|.......|.||.....||
  Rat   110 ASGAALPSASPSGSSSSSSSSASAT------------SASAAAAAAAAAAAAAASSP-------- 154

  Fly   341 HPQLVHGNHQALQQHQQQSWPP----RHYSGS--------WYPTSLSEIPISSA---PNIASVTA 390
                 .|....|.:....|.||    .::|.|        .||..|:|:|..:.   |.:..
  Rat   155 -----AGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQ--- 211

  Fly   391 YASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNI 455
                       |||.....||...||.:       |.|.|  ||
  Rat   212 -----------SPPWRDARLACTPHQGS-------ILLDK--DG--------------------- 235

  Fly   456 GNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFS 520
                        |||  ..|.:|:..||.:|||.||:|.|.....|.|||..:|:.|::::|||.
  Rat   236 ------------KRK--HTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 286

  Fly   521 NRRAKWRREE-------KLRNQRRTPNSTGASATSSSTSATASLTDSPNS 563
            |||.|||::.       |.:....|....|.|.............| |||
  Rat   287 NRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLD-PNS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
		Homeobox	475..527	CDD:278475	24/51 (47%)
Nkx6-1	NP_113925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		23/102 (23%)
		Repressor domain. /evidence=ECO:0000250	102..269		52/249 (21%)
		Homeobox	240..294	CDD:395001	25/53 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		8/42 (19%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		7/30 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910