DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Vax1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_072158.1	Gene:	Vax1 / 64571	RGDID:	621132	Length:	336	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	88/326 - (26%)
Similarity:	127/326 - (38%)	Gaps:	89/326 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   408 ESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKR--- 469
            ||....|.:.:.|.|     ..||..|..|   .||..|:.|...|| .:.:.|..|.||.|
  Rat    28 ESREIKGAEGSLPAA-----FLKEPQGAFS---ASGASEDCNKSKSN-SSADPDYCRRILVRDAK 83

  Fly   470 ---------------KLQRNRTSFTNDQIDSLEKEFERTHYPDVFARER--LAGKIGLPEARIQV 517
                           :.:|.|||||.:|:..||.||:|..|  |..|||  ||.::.|.|.:::|
  Rat    84 GSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQY--VVGRERTELARQLNLSETQVKV 146

  Fly   518 WFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTD--------SPNSLSA----CSSL 570
            ||.|||.|.::::...::.|        :..|.|:||.|:..        ||..|.|    |::.
  Rat   147 WFQNRRTKQKKDQGKDSELR--------SVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATG 203

  Fly   571 LSGSA-GGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDC 634
            ..||| .|||:                  |.||||..:..:..    ...:.|:....|..|:..
  Rat   204 ALGSALRGPSL------------------PALGAGAAAGSAAA----AAAAATAPGPAGAASQHP 246

  Fly   635 RRV---CSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSD 696
            ..|   ..|.|.|.||      :.:......|.|.....|.|      .|::.|.:....|:|:.
  Rat   247 PAVGGAPGPGPAGPGG------LHAGAPTASHGLFSLPVPSL------LGSVASRLSSAPLTMAG 299

  Fly   697 S 697
            |
  Rat   300 S 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	27/53 (51%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39		3/10 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..69		7/22 (32%)
		vax upstream domain	72..99		5/26 (19%)
		homeobox	100..159		28/60 (47%)
		Homeobox	103..156	CDD:278475	27/54 (50%)
		vax downstream domain	178..189		0/10 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..267		8/36 (22%)
		vax terminal domain	315..323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910