Protein Alignment ey and pax6b

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_005168876.1
• Gene: pax6b / 60639
• ZFINID: ZDB-GENE-001031-1
• Length: 450
• Species: Danio rerio
• Alignment Length: 599
• Identity: 249/599 - (41%)
• Similarity: 288/599 - (48%)
• Gaps: 218/599 - (36%)

  Fly    98 HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQ-------------VSNGCVSKI 149
            ||||||||||||.||||||||||||||||||||||||||||||             |||||||||
Zfish    24 HSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHDDAKVQLDNKNVSNGCVSKI 88

  Fly   150 LGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVS 214
            ||||||||||||||||||||||||.|||.||:|||||||||||||||||||.|.|||||||||||
Zfish    89 LGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVS 153

  Fly   215 SINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTAT 279
            ||||||||||::|:|.
Zfish   154 SINRVLRNLASEKQQM------------------------------------------------- 169

  Fly   280 PLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQL 344
                    ||         :.:|:|||:||                   |||    ||..:.|
Zfish   170 --------GA---------DGMYDKLRMLN-------------------GQS----GTWGTRP-- 192

  Fly   345 VHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIES 409
                                   .|||.       :|.|                  ..||.
Zfish   193 -----------------------GWYPG-------TSVP------------------GQPNQ--- 206

  Fly   410 LASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRN 474
                                   ||.|..:.|   |||:|..:||..::::.|.||.||||||||
Zfish   207 -----------------------DGCQQQDNG---GENTNSISSNGEDSDETQMRLQLKRKLQRN 245

  Fly   475 RTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTP 539
            |||||.:||::||||||||||||||||||||.||.||||||||||||||||||||||||||||..
Zfish   246 RTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQA 310

  Fly   540 NSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPS---VSTINGLSSPSTLSTNVNAPTL 601
            :::.:....||:..|:.....|...:..|.......|.|.   .:|..||....:.:...|.|
Zfish   311 SNSSSHIPISSSFNTSVYQAIPQPTTPVSFTTGSMLGRPDTALTNTYTGLPPMPSFTMANNLP-- 373

  Fly   602 GAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSP----------CPLGVGGHQNTHHIQS 656
                           ::||.||       |..|....||          .|..:..|.|:..:.:
Zfish   374 ---------------MQPSQTS-------SYSCMLPSSPSVNGRSFDTYTPPHMQAHMNSQTMAT 416

  Fly   657 NGHAQGHALVPAIS 670
            :|.|....:.|.:|
Zfish   417 SGTASTGLISPGVS 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	116/135 (86%)
		Homeobox	475..527	CDD:278475	45/51 (88%)
pax6b	XP_005168876.1	PAX	23..160	CDD:128645	116/135 (86%)
		Homeobox	246..298	CDD:306543	45/51 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2213
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152885at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.910