Protein Alignment ey and pax2b

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_073773984.1
• Gene: pax2b / 60638
• ZFINID: ZDB-GENE-001030-4
• Length: 401
• Species: Danio rerio
• Alignment Length: 669
• Identity: 180/669 - (26%)
• Similarity: 253/669 - (37%)
• Gaps: 297/669 - (44%)

  Fly    98 HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPR 162
            |.||||||||||.||||||..||:||||||.|.|||||||.|:||:||||||||||||||||:|.
Zfish    16 HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPG 80

  Fly   163 AIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQK 227
            .||||||:|||.:||.||:.|||:.|::||||||||||.|.:|.||.:||||||||::|....|.
Zfish    81 VIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQP 145

  Fly   228 EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNS 292
            ...|. .|:|.::.|::|                            :..||:|..||.|.
Zfish   146 FHPSP-DGTSLSTPGHTI----------------------------IPSTASPPVSSSSN----- 176

  Fly   293 GEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQ 357
                                       :|.
Zfish   177 ---------------------------DPV----------------------------------- 179

  Fly   358 QSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVA 422
                     ||:....:..||.|:                                |.:|
Zfish   180 ---------GSYSINGILGIPRSN--------------------------------GEKR----- 198

  Fly   423 TEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLE 487
                  |::.||.:    ||.:..:|.|...:            |::.|:.:  :||..|:::|:
Zfish   199 ------KRDADGSE----GSAQSSDSQGSVES------------LRKHLRAD--AFTQQQLEALD 239

  Fly   488 KEFERTHYPDVF-----ARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASAT 547
            :.|||..:||||     .:...|.:..||..                           :||....
Zfish   240 RVFERPVFPDVFPTSEHIKPEQASEYSLPAL---------------------------NTGLDEV 277

  Fly   548 SSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPT 612
            ..|.|:           ||.|.|      |.|||.    |.|           :|..:.::..|.
Zfish   278 KPSLSS-----------SAASDL------GASVSQ----SYP-----------VGRDMANTTLPG 310

  Fly   613 PIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNS 677
            ..||:.|:                       |.|.:..             :.:..:.|...|:
Zfish   311 YPPHVPPT-----------------------GQGSYAT-------------STLAGMVPGSEFS- 338

  Fly   678 GSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAV--GPLAPPS---PIPQQGDLTPSSLYPCHM 737
               |..||:..:|  :.::::       .|::.|:  .|.|||.   |:|    :|.:|.:...|
Zfish   339 ---GNPYSHPQYT--TYNEAW-------RFSNPAILMHPEAPPPQLLPLP----MTATSYHANQM 387

  Fly   738 TLRPPPMAPAHH---HIVP 753
            |..      ||.   ||:|
Zfish   388 TRH------AHQLGLHILP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	92/122 (75%)
		Homeodomain	473..528	CDD:459649	14/59 (24%)
pax2b	XP_073773984.1	None