DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxa11a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571619.1	Gene:	hoxa11a / 58061	ZFINID:	ZDB-GENE-000823-8	Length:	315	Species:	Danio rerio

Alignment Length:	283	Identity:	57/283 - (20%)
Similarity:	102/283 - (36%)	Gaps:	74/283 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 VGQSPNHLGTR-------SSHPQLVHGNHQALQQH---QQQSWPPRHYSGSWYPT--SLSEIPIS 380
            :.|||:   ||       |:.||:.|......:.:   ....||.|......||:  |:.:..:.
Zfish    35 LSQSPS---TRPVTYSYASNLPQVQHVREVTFRDYAIDPSTKWPHRGPLAHCYPSEDSVHKECLP 96

  Fly   381 SAPNIASVTAYASGPSLAHSLSPPNDIESL-ASIGHQRNCP----------------------VA 422
            :...:..:....:..:..||.|......:. .::|.....|                      .|
Zfish    97 AVTTVGEMFPKNNASAYYHSTSNTTSASNFYGNVGRNGVLPQAFDQFFDTAYGGSDSVVDNDYAA 161

  Fly   423 TEDIHLKKEL----------DGHQSDETGSGEGENSNGGASNIG-NTEDDQARLILKRKLQ---- 472
            .:.:|..|:.          :|.:..||.|.|..:.|......| |::.:..:.:::..||
Zfish   162 RDKMHSSKQSTPAPAPEQQPEGKERPETSSPESSSGNNEEKTSGANSKYELNKTVMRESLQCCAL 226

  Fly   473 ------------------RNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWF 519
                              :.|..:|..||..||:||..:.|.:...|.:|:..:.|.:.::::||
Zfish   227 LLKFYMLFYKRIGGPRFRKKRCPYTKFQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKMWF 291

  Fly   520 SNRRAKWRREEKLRNQRRTPNST 542
            .|||.|   |:||...|....||
Zfish   292 QNRRMK---EKKLNRDRLQYYST 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
hoxa11a	NP_571619.1	DUF3528	26..164	CDD:288866	21/131 (16%)
hoxa11a	NP_571619.1	Homeobox	246..299	CDD:278475	18/55 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910