DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxa5a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571615.1	Gene:	hoxa5a / 58055	ZFINID:	ZDB-GENE-000823-9	Length:	227	Species:	Danio rerio

Alignment Length:	219	Identity:	63/219 - (28%)
Similarity:	87/219 - (39%)	Gaps:	53/219 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 PRHYSGSW-----YPTSLSEIPIS-SAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCP 420
            |.|:..|.     |..|.:..|:. :.|    |||.::.||..|.     ...|||      |.|
Zfish    22 PGHFLSSGERTQSYKDSPTATPVRYNQP----VTASSAEPSSDHL-----PCSSLA------NSP 71

  Fly   421 VATEDIH--LKKELD---GHQSDETG---SGEG---------ENSNGGASNIGNTEDDQARLIL- 467
            | :|..|  ||..|.   |..|...|   |.||         |....|:....:....:|..|.
Zfish    72 V-SEQSHRALKISLSSTAGSASKSFGTVLSREGVSKVSSSMEEEKPPGSGQTASQNVSEAPQIYP 135

  Fly   468 -KRKL------------QRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWF 519
             .|||            :|.||::|..|...|||||....|.....|..:|..:.|.|.:|::||
Zfish   136 WMRKLHISHDNLAGPEGKRPRTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWF 200

  Fly   520 SNRRAKWRREEKLRNQRRTPNSTG 543
            .|||.||:::.||::.......:|
Zfish   201 QNRRMKWKKDNKLKSMNMAAAGSG 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
hoxa5a	NP_571615.1	Homeobox	155..208	CDD:278475	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910