DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxb6b

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571613.1	Gene:	hoxb6b / 58053	ZFINID:	ZDB-GENE-000823-7	Length:	224	Species:	Danio rerio

Alignment Length:	210	Identity:	53/210 - (25%)
Similarity:	80/210 - (38%)	Gaps:	56/210 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 PRHYSGSWYPTSLSEIPISS--APNIAS---VTAY---------ASGPSLAHSLSPPNDIESLAS 412
            |.:.||  |..||...|.::  |.|:..   .::|         .||.:.|...|.||...|.
Zfish    26 PLYSSG--YTDSLRHYPSATFGATNVQDKVYTSSYYQQAGGVFGRSGSTSACDYSTPNIYRSA-- 86

  Fly   413 IGHQRNCPVATEDIHLKKELDGHQSDETGSG-------------------EGENS-NGGASNIGN 457
               .|:|.:.:.:..|....|..::|.|..|                   :..|| ||...:.|
Zfish    87 ---DRSCAIGSLEDSLVLTQDQCKTDCTEQGTERYFSTEDKPCTPVYPWMQRMNSCNGMPGSTG- 147

  Fly   458 TEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNR 522
                          :|.|.::|..|...|||||....|.....|..::..:.|.|.:|::||.||
Zfish   148 --------------RRGRQTYTRFQTLELEKEFHFNRYLTRRRRIEISHALCLTERQIKIWFQNR 198

  Fly   523 RAKWRREEKLRNQRR 537
            |.||::|.|..|..:
Zfish   199 RMKWKKENKAVNSAK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
hoxb6b	NP_571613.1	Antp-type hexapeptide	129..134		0/4 (0%)
hoxb6b	NP_571613.1	Homeobox	151..203	CDD:278475	19/51 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910