DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxa9b

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571608.1	Gene:	hoxa9b / 58048	ZFINID:	ZDB-GENE-000823-2	Length:	258	Species:	Danio rerio

Alignment Length:	263	Identity:	54/263 - (20%)
Similarity:	88/263 - (33%)	Gaps:	85/263 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 QSPNHLGTR-SSHPQLVHGNHQ--ALQQHQQQSW----PPRHYSGSWYPTSLSEIPISSAPNI-- 385
            ::.:||..| ||.|.:...:.:  .|:..:|:.:    ....:..||.|...:...|:..|.|
Zfish    18 ENDDHLAPRFSSGPVVQQQSRELTLLEYSEQEPYTFQAKSSIFGASWSPVQPTGASIAYHPYIHH 82

  Fly   386 ---------ASVTAYA---------------------------SGPSLAHSL------------- 401
                     |||..:|                           ||....|:|
Zfish    83 PCSTGDSDGASVRPWALEPLPALPFTGLSTDTHQDIKLEPLVGSGECTTHTLLVAETDNNTTQTE 147

  Fly   402 -SPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARL 465
             ..|:|..|..|  |....|..|     |.:||..:.                   |.::..:..
Zfish   148 RKVPDDAVSNGS--HDEKIPAET-----KLDLDPSKC-------------------NQDNPLSNW 186

  Fly   466 ILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREE 530
            :..:..::.|..:|..|...|||||....|.....|..:|..:.|.|.::::||.|||.|.::..
Zfish   187 LHAKSTRKKRCPYTKHQTLELEKEFLFNMYLSRDRRYEVARLLNLTERQVKIWFQNRRMKMKKCN 251

  Fly   531 KLR 533
            |.|
Zfish   252 KDR 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
hoxa9b	NP_571608.1	Hox9_act	1..174	CDD:282473	31/162 (19%)
hoxa9b	NP_571608.1	Homeobox	195..248	CDD:278475	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910