DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and pax1b

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_700877.6	Gene:	pax1b / 572108	ZFINID:	ZDB-GENE-060503-372	Length:	340	Species:	Danio rerio

Alignment Length:	385	Identity:	131/385 - (34%)
Similarity:	173/385 - (44%)	Gaps:	86/385 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSI 159
            |:.:..|||||||||.|||||::.|.:|||||..|.|||||||.|:||:|||||||.||.|||||
Zfish     4 DQTYGEVNQLGGVFVNGRPLPNAIRIRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSI 68

  Fly   160 RPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLA 224
            .|.|||||||||.|..||..|..||:..|.|||||||||||.:.||...|:||||||:|:|||..
Zfish    69 LPGAIGGSKPRVTTPNVVKSIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKI 133

  Fly   225 AQKEQQSTGSGSSS------------------TSAGNSISAKVSVSIG--------GNVSNVASG 263
            ....|.|.....:|                  :..|:.:.:..:||:.        ..|||:. |
Zfish   134 GNLSQPSQYDSKTSPPQISYNPVYPYSYPNTMSPTGSKLGSPPAVSVSLSRAWPSVHTVSNIL-G 197

  Fly   264 SRGTL--------SSSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLE 320
            .|..:        .|....|:..|.:| ..|..:.:...|.::..:...::.  ||.::......
Zfish   198 IRAFMDPAAIAGSESYQPKMEDWTGVN-RPSFPSVHGVNGIDKPPLESDIKY--TQASSNLSGYV 259

  Fly   321 PARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNI 385
            ||.|.....|...:.|         |||:                 |.|...|..    .|.||.
Zfish   260 PACAYSATNQYGVYGG---------HGNY-----------------GHWQSQSAG----LSHPNT 294

  Fly   386 ASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEG 445
            .::   ...|:|..:||..|               .:.|.:..|..|..||.:...:..|
Zfish   295 GTM---IQSPNLHSALSFKN---------------TSREAVERKSPLSKHQHEGLSAVHG 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	83/122 (68%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
pax1b	XP_700877.6	PAX	6..133	CDD:238076	86/126 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910