DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP001493

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_001689344.2	Gene:	AgaP_AGAP001493 / 5667704	VectorBaseID:	AGAP001493	Length:	387	Species:	Anopheles gambiae

Alignment Length:	377	Identity:	132/377 - (35%)
Similarity:	165/377 - (43%)	Gaps:	131/377 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 VNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 165
            |||||||||.|||||:|||.:|||||..|.|||||||.|:||:|||||||.||:|||||.|.|||
Mosquito    42 VNQLGGVFVNGRPLPNSTRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIG 106

  Fly   166 GSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLR----NLA-- 224
            ||||||.|.:||:.|.:.|::.|.|||||||||||.:.||..:|:||||||:|:||    |||
Mosquito   107 GSKPRVTTPKVVTYIRELKQKDPGIFAWEIRDRLLSDGVCDKNNVPSVSSISRILRNKLGNLAHH 171

  Fly   225 ------AQKEQQSTGSGSSSTSAG-----NSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTA 278
                  .......||.|.:.|...     |||......:                         |
Mosquito   172 HHHPHHPHHPHAGTGGGGAHTPHAPAHLYNSIYPSYPYA-------------------------A 211

  Fly   279 TPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQ 343
            :.|.|..|.|.|                         |.|  |..|.|:  :||
Mosquito   212 STLKSEMSCGGS-------------------------PSP--PTGATPI--RSP----------- 236

  Fly   344 LVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASG---PSLAHSLSPPN 405
                       |....||..|        |:::| :::..:.|:|.|..:|   .|..|:..||.
Mosquito   237 -----------HAHCPWPSSH--------SVTDI-LANVHHQATVAALRNGGTPTSQCHTTPPPT 281

  Fly   406 DIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGN 457
            .:                          |.|....|.|.|..:.||.:..||
Mosquito   282 SV--------------------------GGQLMSGGGGNGGGNGGGGAGNGN 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	84/119 (71%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
AgaP_AGAP001493	XP_001689344.2	PAX	39..162	CDD:128645	84/119 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910