DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and pax1a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001074061.1	Gene:	pax1a / 564359	ZFINID:	ZDB-GENE-070112-182	Length:	359	Species:	Danio rerio

Alignment Length:	200	Identity:	102/200 - (51%)
Similarity:	125/200 - (62%)	Gaps:	26/200 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSI 159
            ::.:..|||||||||.|||||::.|.:|||||..|.|||||||.|:||:|||||||.||.|||||
Zfish     7 EQTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSI 71

  Fly   160 RPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLA 224
            .|.|||||||||.|..||..|..||:..|.|||||||||||.:.||...|:||||||:|:|||..
Zfish    72 LPGAIGGSKPRVTTPNVVKNIRDYKQSDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKI 136

  Fly   225 AQKEQ------------QSTGS---------GSSSTSAGNSISAKVSVSI-GGNVSNVASGSRGT 267
            ....|            ||:.|         .::.:.:|..:|:...|.: ||:||.    |||.
Zfish   137 GNLSQPNPYENGKQAPPQSSLSYNHIYPYSYPNAMSPSGTKMSSPPGVPVTGGHVSI----SRGW 197

  Fly   268 LSSST 272
            .|:.|
Zfish   198 PSAHT 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	83/122 (68%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
pax1a	NP_001074061.1	PAX	9..136	CDD:238076	86/126 (68%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910