DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and drgx

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001032182.1	Gene:	drgx / 560399	ZFINID:	ZDB-GENE-070330-1	Length:	287	Species:	Danio rerio

Alignment Length:	332	Identity:	101/332 - (30%)
Similarity:	135/332 - (40%)	Gaps:	91/332 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   444 EGE-------NSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFAR 501
            |||       |:||..::.....||.   .|:||.:||||:||..|:::||..|.:|||||||||
Zfish    11 EGECCRTNTLNTNGFGNHASGDFDDG---FLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFAR 72

  Fly   502 ERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATA-SLTDSPNSLS 565
            |.||.||.|.|||:||||.|||||||:.|     |.|....|.....:..:..| :|..||
Zfish    73 EELAMKINLTEARVQVWFQNRRAKWRKTE-----RGTSEQDGGKEQMNEGNPPARNLNQSP---- 128

  Fly   566 ACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDN--DNG 628
                          |........|..|..|:|. .:|:|     .|     ..|||....  :..
Zfish   129 --------------VDHSRSKKEPMELQQNINR-VVGSG-----GP-----FFPSCLPGTLLNTA 168

  Fly   629 RQSEDCRRV-----------CSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGA 682
            ..::...:|           |.|.|:|: .....:..|||..|...||                .
Zfish   169 TYAQALSQVATLKGSPLCSCCVPDPMGL-SFLPPYGCQSNRTASVAAL----------------R 216

  Fly   683 MYSNMHHTALSMSDSY---GAVTPIPSFNHSAVGPLAPPS-PIPQQ--GDLTPSSLYPCHMTLRP 741
            |.:..|..|:..|.:.   |:.|          ||.|.|: |:.|.  ||.:|:|..|...:||.
Zfish   217 MKAREHSEAVLQSANLLGTGSTT----------GPAAGPALPLSQNTGGDSSPNSSTPKITSLRR 271

  Fly   742 PPMAPAH 748
            .|....|
Zfish   272 TPDKHLH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	35/51 (69%)
drgx	NP_001032182.1	Homeobox	46..98	CDD:278475	35/51 (69%)
drgx	NP_001032182.1	OAR	207..223	CDD:281777	5/31 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910