DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and lmx1ba

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001349521.1	Gene:	lmx1ba / 554361	ZFINID:	ZDB-GENE-050114-3	Length:	375	Species:	Danio rerio

Alignment Length:	335	Identity:	73/335 - (21%)
Similarity:	121/335 - (36%)	Gaps:	70/335 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 LGTRSSHPQLV-HGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSL- 397
            ||...:|.|.| .|.|:.:...    :..|....||:...|.   .|....:.:::.|:....|
Zfish    22 LGADCAHHQSVCEGCHRPISDR----FLLRMNDSSWHEECLQ---CSVCQQLLTMSCYSRDHKLY 79

  Fly   398 ----------------AHSLSPPNDI-ESLASIGH----------QRNCP-----------VATE 424
                            ...:||...: .:|.|:.|          :|.|.           :...
Zfish    80 CKHDYQQLFATKCSGCLEKISPTELVMRALESVYHLSCFCCCVCERRLCKGDEFVLKEGQLLCKT 144

  Fly   425 DIHLKKELDGHQSDETGSGEGEN----SNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDS 485
            |...:|:|......::...|.|:    ...||...|...||...   .|:.:|.||..|..|..:
Zfish   145 DYEREKDLASPDLSDSDKSEDEDLDVKPEKGAGGQGKGSDDSKD---PRRPKRPRTILTTQQRRA 206

  Fly   486 LEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR-------EEKLRNQRRTPNSTG 543
            .:..||.:..|....||.||.:.||....:||||.|:|||.::       :::.:|.:|......
Zfish   207 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQEQQNSQRLGQDVM 271

  Fly   544 ASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTI-NGLSSPSTLSTNVNA---PTLGAG 604
            :|...:..|:...|...|.     .:|:|..:.|.|.... .||:.|.....::|.   .::...
Zfish   272 SSRMENLMSSYTPLAPPPP-----HALVSMESSGYSTDPFQQGLTPPQMPGDHMNPYGNDSIFHD 331

  Fly   605 IDSSESPTPI 614
            |||..|.|.:
Zfish   332 IDSDTSLTSL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
lmx1ba	NP_001349521.1	LIM1_Lmx1b	33..85	CDD:188757	9/58 (16%)
		LIM	92..146	CDD:295319	7/53 (13%)
		Homeobox	195..248	CDD:306543	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910