DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and barhl1a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001017712.2	Gene:	barhl1a / 550407	ZFINID:	ZDB-GENE-050417-212	Length:	299	Species:	Danio rerio

Alignment Length:	350	Identity:	81/350 - (23%)
Similarity:	130/350 - (37%)	Gaps:	94/350 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 ISAKVSVSIGGNVSNVASG---SRGTLSSSTDLMQTATPLNSSESGGAS--NSGEGSEQEAIYEK 304
            :|...|..|...:|:.||.   |:|...|..:|    :|.:..:||.:|  :....|.::|:..:
Zfish     3 VSNGSSFGIESILSHRASSPCMSKGECRSPAEL----SPRSDLDSGCSSPPSPRRSSVEDAVQRR 63

  Fly   305 LRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSW 369
            .|.|                                      |....||..||    ||..:.|:
Zfish    64 ARAL--------------------------------------GLDSPLQISQQ----PRTVTSSF 86

  Fly   370 YPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDG 434
            .   :.:|.....| :|:...|:|....|      .|.|......|..:.  :..:..:|.|.|
Zfish    87 L---IRDILADCKP-LAACAPYSSTGQSA------QDAEDCMDKLHSNSS--SDSEYRVKDEAD- 138

  Fly   435 HQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVF 499
              .:.:.|.:..||               ||   :|.::.||:||:.|:..||:.|||..|..|.
Zfish   139 --REISSSRDSPNS---------------RL---KKPRKARTAFTDHQLAQLERSFERQKYLSVQ 183

  Fly   500 ARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSL 564
            .|..||..:.|.:.:::.|:.|||.||:|:        |.......|.:.:.||...:..||...
Zfish   184 DRMELAASLNLTDTQVKTWYQNRRTKWKRQ--------TAVGLELLAEAGNYSALQRMFPSPYFY 240

  Fly   565 SACSSLLSGSAGGPSVSTINGLSSP 589
            .  .||:|....||.:....|.|:|
Zfish   241 P--QSLVSNLDPGPGLYLYRGPSAP 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
barhl1a	NP_001017712.2	TPP_enzymes	<122..177	CDD:294952	19/77 (25%)
barhl1a	NP_001017712.2	Homeobox	159..211	CDD:278475	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910