DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and hoxd1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001016678.1	Gene:	hoxd1 / 549432	XenbaseID:	XB-GENE-482731	Length:	301	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	62/275 - (22%)
Similarity:	96/275 - (34%)	Gaps:	93/275 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 YPTSLSE---IPISSAPNIASVTAYASGPSL--------AHSLSPPNDIESLASIGHQRNCPVAT 423
            ||.|.::   :|:...|...:..|....|:|        |:...||:|...|.|         :|
Frog    33 YPGSGADHPFMPVGGVPGSVAHQASHQSPALYAPCSLDVAYEPPPPSDYSFLHS---------ST 88

  Fly   424 E-----DIHLKKELDGH----QSDETGSGE------------GENS----------------NGG 451
            :     ..||.:|..||    .|...|:|.            ||.:                .|.
Frog    89 DYDYYGSNHLVEETGGHIPYGSSVFPGNGSYILNGQLSYRTLGEETQMAQIAQCKEPLEVYPGGN 153

  Fly   452 ASNIGNT-----------EDDQARLILKRKLQRN-------------------RTSFTNDQIDSL 486
            ..:|..:           .|.........|::||                   ||:||..|:..|
Frog   154 LQSISPSPGTYPKPASPASDTHVSTFDWMKVKRNPPKKSLQSEYGVASPPCTVRTNFTTKQLTEL 218

  Fly   487 EKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASA----- 546
            ||||....|.....|..:|..:.|.:.::::||.|||.|.::.|:..:...:|.|..||:
Frog   219 EKEFHFNKYLTRARRIEIANSLQLNDTQVKIWFQNRRMKQKKREREGSLPNSPPSGPASSICVKT 283

  Fly   547 -TSSSTSATASLTDS 560
             .|.|...||:|:.|
Frog   284 PLSKSVHETATLSPS 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/51 (39%)
hoxd1	NP_001016678.1	Antp-type hexapeptide. /evidence=ECO:0000255	178..183		0/4 (0%)
		Homeobox	207..260	CDD:365835	20/52 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..301		13/44 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910