DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and lhx5

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001016082.1	Gene:	lhx5 / 548836	XenbaseID:	XB-GENE-490400	Length:	402	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	76/315 - (24%)
Similarity:	103/315 - (32%)	Gaps:	109/315 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 SLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQS 437
            |.|.:..||..:::|.|        ..||||  |::.          |:..|    .||.|...|
Frog   121 SASSLKESSLNSVSSCT--------DRSLSP--DLQD----------PIQDE----SKETDHSTS 161

  Fly   438 D--ETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFA 500
            .  ||.:.|.|..|.|....|                 .||:....|:::|:..|..|..|....
Frog   162 SDKETANNENEEQNSGTKRRG-----------------PRTTIKAKQLETLKAAFAATPKPTRHI 209

  Fly   501 RERLAGKIGLPEARIQVWFSNRRAKWRREEKL-----------RNQRRT---------------- 538
            ||:||.:.||....|||||.|||:|.||.::|           |:.||.
Frog   210 REQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESDILSSG 274

  Fly   539 ---------------------PNSTGASATSSSTSATASLTDSPNS--LSACSSLLSGSAGGPSV 580
                                 |:...:|.|.|...::......|.|  |....|.|||.....:.
Frog   275 PYSYYGDYQGDYYGSGNYDFFPHGPPSSQTQSPADSSYLQNSGPGSTPLGPLESQLSGHHPSENQ 339

  Fly   581 STINGLSSPSTLS-----TNVNAPTLGAGIDSSESPT-----------PIPHIRP 619
            ...:.:|.|.|.|     |....|..|.......||.           |:||..|
Frog   340 RYADMISHPDTPSPEPSMTGSLHPISGEVFSGGPSPPFSMSNNSGFSGPLPHQNP 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
lhx5	NP_001016082.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753
		LIM2_Lhx1_Lhx5	64..119	CDD:188761
		Homeobox	183..237	CDD:365835	22/53 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910