DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and Rhox7a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001020257.2	Gene:	Rhox7a / 547168	MGIID:	3580246	Length:	281	Species:	Mus musculus

Alignment Length:	253	Identity:	63/253 - (24%)
Similarity:	89/253 - (35%)	Gaps:	51/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   486 LEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASA---- 546
            :|..|:.|.||||..||.||..:...||::|:.|:|||||.|..||....|.|   .||.|
Mouse     1 METMFQETQYPDVLTREVLARSMDGSEAKVQIRFNNRRAKQRAREKKAMLRST---AGAKAPLVL 62

  Fly   547 -TSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSES 610
             .....:...|...|...|            |.|.:...|:..|..|..........:.:|:|
Mouse    63 PAGEERNGEDSRDQSSPGL------------GASAAEWGGVEGPGELGRKEKNGASPSAVDTS-- 113

  Fly   611 PTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNF 675
                 .:|...|....:|...::.||..:..|....|.::.|.:.        .|||....|...
Mouse   114 -----GVRGDWTQKGASGSSQKNERRPQNRVPECRWGTEDVHPVP--------VLVPRAQRRQRV 165

  Fly   676 NSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPI------PQQGDL 727
            .|.|.|.          |:|.....:.|:.......|..|.|..|:      ||..:|
Mouse   166 GSRSRGQ----------SVSLKCPRIRPVLVSTVQPVPVLVPHRPLRDGFTEPQLQEL 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/40 (50%)
Rhox7a	NP_001020257.2	Homeobox	<1..42	CDD:278475	20/40 (50%)
Rhox7a	NP_001020257.2	homeodomain	202..257	CDD:238039	3/12 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910