Protein Alignment ey and Pax5

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_038966491.1
• Gene: Pax5 / 500453
• RGDID: 1565236
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 169/560 - (30%)
• Similarity: 220/560 - (39%)
• Gaps: 226/560 - (40%)

  Fly    98 HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPR 162
            |.||||||||||.||||||..||:||||||.|.|||||||.|:||:||||||||||||||||:|.
  Rat    17 HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPG 81

  Fly   163 AIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQK 227
            .||||||:|||.:||.||::|||:.|::||||||||||.|.||.||.:||||||||::|....|.
  Rat    82 VIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQP 146

  Fly   228 EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNS 292
            ..|...:.|.|..:..|::         .||:|::.|.|:..|.:.::...:|        ::::
  Rat   147 PNQPVPASSHSIVSTGSVT---------QVSSVSTDSAGSSYSISGILGITSP--------SADT 194

  Fly   293 GEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQ 357
            .:....|.|.|
  Rat   195 NKRKRDEGIQE------------------------------------------------------ 205

  Fly   358 QSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVA 422
                                  |..||             .||| |..|.
  Rat   206 ----------------------SPVPN-------------GHSL-PGRDF--------------- 219

  Fly   423 TEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLE 487
                 |:|::.|                                         ..||..|::.|:
  Rat   220 -----LRKQMRG-----------------------------------------DLFTQQQLEVLD 238

  Fly   488 KEFERTHYPDVFA---------------RERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRR 537
            :.|||.||.|:|.               |:.||    .|:|   |.|                :.
  Rat   239 RVFERQHYSDIFTTTEPIKPEQWCPVLMRQYLA----QPQA---VLF----------------QT 280

  Fly   538 TPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTL---------- 592
            |..|..||...|.....|:|| ||......||:    .|..|...:.|....||.
  Rat   281 TEYSAMASLAGSLDDMKANLT-SPTPADIGSSV----PGPQSYPIVTGRDLASTTLPGYPPHVPP 340

  Fly   593 --STNVNAPTLGAGIDSSE-SPTPIPHIRPSCTSDNDNGR 629
              ..:.:||||...:..|| |.:|..|  |..:|.||:.|
  Rat   341 AGQGSYSAPTLTGMVPGSEFSGSPYSH--PQYSSYNDSWR 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	93/122 (76%)
		Homeobox	475..527	CDD:278475	18/66 (27%)
Pax5	XP_038966491.1	PAX	16..140	CDD:128645	93/122 (76%)
		Pax2_C	298..408	CDD:403565	26/88 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010