DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Emx1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_575584.5	Gene:	Emx1 / 500235	RGDID:	1564002	Length:	290	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	80/294 - (27%)
Similarity:	113/294 - (38%)	Gaps:	103/294 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 SSSTDLMQTAT----PLNS--SESGGASNS----GEGSEQEAI---YEKLR--LLNTQHAAGPGP 318
            |::..:.|.||    .:.|  ::.||...|    |.||...|:   .|.||  .||..|   |..
  Rat    29 SAAATMFQPATKRGFTIESLVAKDGGTGGSPGSGGAGSHPLAVAASEEPLRPTALNYPH---PSA 90

  Fly   319 LEPA-----RAAPLVGQSPNHLGTRSSHPQLVHG---NHQALQQHQQQSWPPRHYSGSWYPTSLS 375
            .|.|     .||...|.|.:..|    .|:||..   ||.||..|      |.|..||
  Rat    91 AETAFVSGFPAAAAAGASRSLYG----GPELVFPEAMNHPALTVH------PAHQLGS------- 138

  Fly   376 EIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIH-----LKKELDGH 435
                                   .||.||:   |..|..|:       :.:|     |:....||
  Rat   139 -----------------------SSLQPPH---SFFSAQHR-------DPLHFYPWVLRNRFFGH 170

  Fly   436 QSDETGSGEGENSNGGASNIGNTEDDQARLIL----KRKLQRNRTSFTNDQIDSLEKEFERTHYP 496
            :...                  :|..|..|:|    .||.:|.||:|:..|:..||:.||:.||.
  Rat   171 RFQA------------------SEVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYV 217

  Fly   497 DVFARERLAGKIGLPEARIQVWFSNRRAKWRREE 530
            ....|::|||.:.|.|.:::|||.|||.|::|::
  Rat   218 VGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQK 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	23/51 (45%)
Emx1	XP_575584.5	COG5576	141..>251	CDD:227863	41/137 (30%)
Emx1	XP_575584.5	Homeobox	196..248	CDD:278475	23/51 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910