DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and Dr

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_477324.1	Gene:	Dr / 45285	FlyBaseID:	FBgn0000492	Length:	515	Species:	Drosophila melanogaster

Alignment Length:	474	Identity:	106/474 - (22%)
Similarity:	157/474 - (33%)	Gaps:	166/474 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 SSSTSAGNSISAKVSVSIGGNV-SNVASGSRGTLSSSTDLMQT--------ATPLNSS------- 284
            ||:|.|||.|....|.:.|.|. ||::||:. |.|:.|:|..:        |:|.:.|
  Fly    26 SSNTPAGNLIITSSSSNSGSNSGSNMSSGNM-TSSNLTNLSPSHPAGLNALASPTSPSALLLAHQ 89

  Fly   285 ----ESGGASNSGEGSEQEAIYEKL---------------RLLN----------------TQHAA 314
                :........:..:|:|...:|               ||.|                .|.|.
  Fly    90 QHLLQQHQQHQQQQQQQQQAAALQLAAVHPPAHHLHKTTSRLSNFSVASLLADTRPRTPPNQAAD 154

  Fly   315 GP------------------GPLEPARAAPLVGQSPNHLGTRSSHPQLV---------HGNHQA- 351
            ||                  .|..||.||..|..:..|....:.|..|:         |..|||
  Fly   155 GPQNLTSSAATSPISQASSTPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAM 219

  Fly   352 ---LQQHQQQ-----SWPPRHYSGSWYPTSLSEIPISSAPNIASVTA--YASGPSLAHSLSPPN- 405
               |:|.|||     :.||...|.:...|.|.. .:.|..|:||..|  ....|..:|:.|...
  Fly   220 AAQLRQQQQQADARANSPPASTSSTPSSTPLGS-ALGSQGNVASTPAKNERHSPLGSHTDSELEY 283

  Fly   406 --------------------DIESLASIGHQRNCPVATE--------------DIHLKKEL---- 432
                                |||.:.:....|:.|...:              ..|::..:
  Fly   284 DEEMLQDHEADHDEEEDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPA 348

  Fly   433 ---DGHQSDE--------------TGSGEGENSNG--------------GASNIGNTEDDQARL- 465
               .||....              ||.|.|....|              || ..|...::..|:
  Fly   349 ALASGHVPIRPTPFSALAAAAVAWTGMGGGVPWPGTRQMPPFGPPGMFPGA-GFGGDANEPPRIK 412

  Fly   466 --ILKRKLQRN-RTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWR 527
              :.|.|..|. ||.||..|:.||||:|....|..:..|...:..:.|.|.::::||.|||||.:
  Fly   413 CNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAK 477

  Fly   528 REEKLRNQRRTPNSTGASA 546
            |.::...::....:.|..|
  Fly   478 RLQEAEIEKIKMAALGRGA 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
Dr	NP_477324.1	Homeobox	424..477	CDD:278475	21/52 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910