DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and tin

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_524433.1	Gene:	tin / 42536	FlyBaseID:	FBgn0004110	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	94/430 - (21%)
Similarity:	155/430 - (36%)	Gaps:	140/430 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 QKEQQSTGSG------SSSTSAGNSISAKVSVSIGGNVSNVAS---------GSRGTLSSSTDLM 275
            |..||...||      :.|.|.|:..:|....:...:|.::.:         ||.|.:..:.
  Fly     3 QHHQQQAQSGGYYDHYTQSPSPGSLTNADALNTTPFSVKDILNMVNQTEAYEGSYGHIDGAA--- 64

  Fly   276 QTATPLNSSESGGASN-----SGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHL 335
             ||:.|.:  :|...|     :.:..:|..:....:.|:.|| ...|....:..:||:...|:.|
  Fly    65 -TASALFA--AGEYQNPHQYLNHQQHQQSELPIPQQQLHHQH-LDDGATTSSSLSPLLPPPPHQL 125

  Fly   336 -------GTRSSHPQLVHGN-HQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYA 392
                   |..:...|..||: ||:.|           :|.|.|..|.|:....     ||.|||.
  Fly   126 YGGYQDYGMPAHMFQHHHGHPHQSFQ-----------HSASAYNMSASQFYAG-----ASATAYQ 174

  Fly   393 SGPSLAHSLSPPNDI---ESLASIGHQRN-------CPVATEDIHLKKELDGHQSD--------- 438
            :..:..::.:...::   .:.:::|.:..       .|..|.|::...|:|..|:.
  Fly   175 TPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPSPTLDLNSSAEVDSLQAPTQKLCVNPL 239

  Fly   439 -----ET-----------GSGEG-----------------ENSNGGASNIG-NTEDDQARLILKR 469
                 ||           ||.||                 :||..|.||.| |:...:.|  :||
  Fly   240 SQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPR--MKR 302

  Fly   470 KLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREE---- 530
            |   .|..|:..|:..||..|....|.....||.:|.|:.|...::::||.|||.|.:|.:
  Fly   303 K---PRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDCE 364

  Fly   531 ------KLRNQRRTPNSTGASATSSSTSATASLTDSPNSL 564
                  ||:::.                     .|||.||
  Fly   365 GIAKHLKLKSEP---------------------LDSPTSL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
tin	NP_524433.1	HOX	301..357	CDD:197696	21/58 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I3587
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910