DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and si:dkey-43p13.5

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_002661267.2	Gene:	si:dkey-43p13.5 / 407678	ZFINID:	ZDB-GENE-131121-510	Length:	315	Species:	Danio rerio

Alignment Length:	273	Identity:	77/273 - (28%)
Similarity:	111/273 - (40%)	Gaps:	76/273 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 PPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHS-----LSPPNDIESLASIGHQRNCP 420
            |..|:    :|...|.:   |:|.|     :..||.|::.     |.|....:||....|..:
Zfish    76 PAAHF----FPAFPSRL---SSPQI-----FIPGPLLSYELLRSYLQPEPCKQSLLLAAHPSS-- 126

  Fly   421 VATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDS 485
                         ||.:|               ||     |:.|.:.:|:.:.|.:|:   |::.
Zfish   127 -------------GHPAD---------------NI-----DEPRPVKQRRARANYSSW---QLEE 155

  Fly   486 LEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTG--ASATS 548
            |||.|:.|||||:|.||.||.::.|.|||:||||.|||||.||:.||:.|      ||  .|...
Zfish   156 LEKTFQSTHYPDIFMREALALRLDLIEARVQVWFQNRRAKMRRQLKLQIQ------TGEQCSQRD 214

  Fly   549 SSTSATASLTDSP----NSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSE 609
            :.|....|...:|    ||.|.|     ........:..:...|||.    :.:|......|..:
Zfish   215 TDTRHPESSISNPELHNNSPSPC-----WDRNQDRTNPAHPKPSPSA----IQSPVTDLLQDQQD 270

  Fly   610 SPTPIPHIRPSCT 622
            ...|.|....||:
Zfish   271 PEAPGPEDLRSCS 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	29/51 (57%)
si:dkey-43p13.5	XP_002661267.2	Homeobox	145..197	CDD:278475	30/54 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910