DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and prrx1a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_999899.1	Gene:	prrx1a / 406431	ZFINID:	ZDB-GENE-020905-5	Length:	245	Species:	Danio rerio

Alignment Length:	235	Identity:	79/235 - (33%)
Similarity:	119/235 - (50%)	Gaps:	33/235 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 SLAHSL----SPPNDIES--LASIGH---QRNCPVA-TEDIHLKKELDGHQSDETGSGEGEN--- 447
            |.||.:    :.||.:|:  .|:..|   ::|..|: ..|:...:|:.|.|::|:....|.:
Zfish     4 SYAHVMDRQATLPNRLETAITANQDHLQAKKNFSVSHLLDLEEAREMVGAQAEESAGEAGRSMLE 68

  Fly   448 SNGGASNIGNTEDDQARLIL----KRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKI 508
            |.|..|....|:.:..:|..    |||.:||||:|.:.|:.:||:.||||||||.|.||.||.::
Zfish    69 SPGLTSGSDTTQQENEQLNAEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRV 133

  Fly   509 GLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDS--PNSLSACSSLL 571
            .|.|||:||||.|||||:|     ||:|....|..||...|.:....::...  |......:..|
Zfish   134 NLTEARVQVWFQNRRAKFR-----RNERAMLASKNASLLKSFSGEVTAVEQPIVPRPAPRPNDYL 193

  Fly   572 S-GSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSES 610
            | ||:  ||.|.:      :|.|.:....|...|::.:.|
Zfish   194 SWGSS--PSYSAM------ATYSPSCANNTTAQGMNMANS 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
prrx1a	NP_999899.1	Homeobox	101..152	CDD:278475	31/50 (62%)
prrx1a	NP_999899.1	OAR	220..237	CDD:281777	1/6 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910