DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and otp

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001286654.1	Gene:	otp / 37364	FlyBaseID:	FBgn0015524	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	431	Identity:	113/431 - (26%)
Similarity:	167/431 - (38%)	Gaps:	160/431 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 SLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPV--ATEDIHL------- 428
            |..::|:  .||:|.:...|.|.                  |.....||  ....:|:
  Fly    31 SFGQLPV--GPNLADLGGGAGGG------------------GSSGGVPVGGGVARLHISGGLCDN 75

  Fly   429 KKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERT 493
            ...|:| .:..:|:|.|.|:||..:| .|:...|.:.:.|.|.:|:||.||..|::.||:.|.:|
  Fly    76 SNALNG-GNGSSGNGNGNNNNGNGNN-NNSMQQQDQHLDKNKQKRHRTRFTPAQLNELERCFSKT 138

  Fly   494 HYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNST---------GASAT-- 547
            ||||:|.||.:|.:|||.|:|:||||.||||||::.:|..|..|||.:.         ||:.|
  Fly   139 HYPDIFMREEIAMRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRTPGALLPSHGLPPFGANITNI 203

  Fly   548 -------------------------------SSSTSATASLTDSPNS-LSACSSLLSGS------ 574
                                           :.|:..::||....|| ::..|:|.:||
  Fly   204 AMGDGLCGTGMFGGDRWSVGVNPMTAGFGQLNQSSPLSSSLNSGLNSGINMGSALGAGSYQHYGL 268

  Fly   575 -AGGPSV---STINGLS-----SPS-TLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGR 629
             |.|.|:   .::.|:|     ||| |...|:|:       .||.:|.|: ..:|:.:.:..||
  Fly   269 NALGDSMMYQHSVGGVSCGPSGSPSATTPPNMNS-------CSSVTPPPL-SAQPNSSQNELNG- 324

  Fly   630 QSEDCRRVCSPCPLGVGGHQNTH-HIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALS 693
                     .|.||.....|.|| |.|...|                           .||
  Fly   325 ---------EPMPLHQQQQQQTHQHQQQQTH---------------------------QHH---- 349

  Fly   694 MSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYP 734
                                |:|||:|..||..|..|...|
  Fly   350 --------------------PMAPPTPTQQQQQLPQSMQSP 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	31/51 (61%)
otp	NP_001286654.1	Homeobox	119..167	CDD:278475	26/47 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450841
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840