DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Alx3

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001007013.2	Gene:	Alx3 / 365900	RGDID:	1359270	Length:	343	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	116/461 - (25%)
Similarity:	153/461 - (33%)	Gaps:	164/461 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 AAGP--GPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTS-- 373
            |.||  ||...||     .::|...||..:.|.|             :..|||....|.:|..
  Rat    10 AVGPAAGPYAAAR-----DEAPGPQGTPDAAPHL-------------RPAPPRGPRLSRFPACGP 56

  Fly   374 -LSEIPISSAPNIASVTAYASGPSL--AHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGH 435
             ...:|..:.|....:.....||.|  .|.....::.|..||        .|.....|..:..|.
  Rat    57 LEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYKGSSEAEEKAS--------KAASFPQLPVDCRGG 113

  Fly   436 QSDETGSGEGENSNGGASNIGNT----------------EDDQARLILKRKLQRNRTSFTNDQID 484
            ..|            |.||:..:                .|.......|.|.:||||:|:..|::
  Rat   114 PRD------------GPSNVQGSPGPCLASLSVPLSPGLPDSMELAKSKSKKRRNRTTFSTFQLE 166

  Fly   485 SLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLR--NQRRTPNSTG---- 543
            .|||.|::||||||:|||:||.:..|.|||:||||.|||||||:.|:..  .:.|.|.:|.
  Rat   167 ELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTTAYDIS 231

  Fly   544 -ASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDS 607
             ...|.|......||..||.         |||.|||.:....|:.||..
  Rat   232 VLPRTDSHPQLQNSLWSSPG---------SGSPGGPCLMPPEGIPSPCM---------------- 271

  Fly   608 SESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPR 672
                :|..|                                       |:|:..|...||| ||
  Rat   272 ----SPYSH---------------------------------------SHGNVAGFMGVPA-SP- 291

  Fly   673 LNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHM 737
                 .:...:||                  |..|..:..|....|||   .||....||....|
  Rat   292 -----AAHPGIYS------------------IHGFPPALGGHSFEPSP---DGDYKSPSLVSLRM 330

  Fly   738 TLRPPP 743
            ..:.||
  Rat   331 KPKEPP 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
Alx3	NP_001007013.2	Homeobox	157..210	CDD:395001	33/52 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910