DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Gsx2

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001131035.2	Gene:	Gsx2 / 364140	RGDID:	1308047	Length:	305	Species:	Rattus norvegicus

Alignment Length:	342	Identity:	79/342 - (23%)
Similarity:	126/342 - (36%)	Gaps:	95/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 TGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGS 296
            :|.|..|..:|......:.|:...:.|...:|:.|..:.:.         .::.:||....|.|:
  Rat    46 SGPGCPSRKSGAFCVCPLCVTSHLHSSRPPAGAGGGATGTA---------GAAVAGGGVAGGTGA 101

  Fly   297 EQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWP 361
                    |.||.:|.:.|||   .|:..|           |.||   .|.:|.|.|.|.....|
  Rat   102 --------LPLLKSQFSPGPG---DAQFCP-----------RVSH---AHHHHHAPQHHHHHHQP 141

  Fly   362 PRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGH-QRNCPV-ATE 424
            .:                   |..|:..|.|:..:.|          :.|::|| |.:.|| |..
  Rat   142 QQ-------------------PGSAAAAAAAAAAAAA----------AAAALGHPQHHAPVCAAT 177

  Fly   425 DIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKE 489
            ..::......|.....||...:..||                     :|.||:||:.|:..||:|
  Rat   178 TYNVSDPRRFHCLTMGGSDTSQVPNG---------------------KRMRTAFTSTQLLELERE 221

  Fly   490 FERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEK--LRNQRRTPNSTGASATSSSTS 552
            |....|.....|..:|..:.|.|.::::||.|||.|.::|.|  .||..       ||.....:.
  Rat   222 FSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGASRNNH-------ASCKCVGSQ 279

  Fly   553 ATASLTDSPNSLSACSS 569
            |..:.::..:|||..|:
  Rat   280 AHYARSEDEDSLSPASA 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	20/51 (39%)
Gsx2	NP_001131035.2	Homeobox	207..260	CDD:395001	20/52 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910