DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Gsc2

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001102316.1	Gene:	Gsc2 / 363831	RGDID:	1305333	Length:	214	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	66/237 - (27%)
Similarity:	97/237 - (40%)	Gaps:	34/237 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 LRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSW 369
            ||||.          .|.......|.:.:|.......|..:.....:|.:.:..:.||:...|.
  Rat     4 LRLLR----------RPPAGMATAGSAASHRDPGRPCPFSIEHILSSLPERRPVARPPQPVGGR- 57

  Fly   370 YPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDG 434
            .|....| |.:.||...........|..|    |....|:.:..|.:...|     :.|..|
  Rat    58 NPAEPDE-PEAPAPAAPCACCCCCNPRAA----PRGTPETASGPGLRLGWP-----LRLAPE--- 109

  Fly   435 HQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVF 499
            ..|..|....|..:..|.|..|.          :|:.:|:||.|:.:|:.:||..|.:..||||.
  Rat   110 SPSPLTAPSTGSPALTGTSGPGP----------QRRTRRHRTIFSEEQLQALEALFVQNQYPDVG 164

  Fly   500 ARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNS 541
            .|||||.:|.|.|.|::|||.|||||||.::::.:.|..|.|
  Rat   165 TRERLAVRIRLREERVEVWFKNRRAKWRHQKRVSSSRLAPGS 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	28/51 (55%)
Gsc2	NP_001102316.1	Homeobox	139..193	CDD:395001	29/53 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910