DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and eve

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_523670.2	Gene:	eve / 36039	FlyBaseID:	FBgn0000606	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	110/518 - (21%)
Similarity:	165/518 - (31%)	Gaps:	207/518 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 GTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHS 400
            |.|:.:.:..|.:|.|                         .|:...|.:..:.|...|..   .
  Fly     3 GYRTYNMESHHAHHDA-------------------------SPVDQKPLVVDLLATQYGKP---Q 39

  Fly   401 LSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARL 465
            ..||:..|.|:|                                .:||..|:.......|...|
  Fly    40 TPPPSPNECLSS--------------------------------PDNSLNGSRGSEIPADPSVR- 71

  Fly   466 ILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREE 530
                   |.||:||.||:..|||||.:.:|.....|..||.::.|||:.|:|||.|||.|.:|:
  Fly    72 -------RYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQ- 128

  Fly   531 KLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGP----SVSTINGLSSPST 591
                  |...:...:|..|..:..||:      |.|.::    |.|.|    :.:.....::.:.
  Fly   129 ------RIAVAWPYAAVYSDPAFAASI------LQAAAN----SVGMPYPPYAPAAAAAAAAAAA 177

  Fly   592 LSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQS 656
            ::||   |.:..|:    .|..:|.: |:                      :.:.||
  Fly   178 VATN---PMMATGM----PPMGMPQM-PT----------------------MQMPGH-------- 204

  Fly   657 NGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPI 721
            :||| ||                                                      |||.
  Fly   205 SGHA-GH------------------------------------------------------PSPY 214

  Fly   722 PQQGDLTPSSLYPCHMTLRPPPMAPA----HH-HIVPGDGGRPAGVGLGSGQSANLGASCSGSGY 781
            .|.      ...|.|:..||.|..||    || |::   |....|....:|.:..|||..|.:.|
  Fly   215 GQY------RYTPYHIPARPAPPHPAGPHMHHPHMM---GSSATGSSYSAGAAGLLGALPSATCY 270

  Fly   782 EVLSA----YALPPPPMASSSAADS---SFSAASSASANVTPHHTIAQES----CPSPCSSAS 833
            ..|..    ...||..:.|||:..|   |.|...|..|.|.....:||.:    .|:|.::.|
  Fly   271 TGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTS 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	26/51 (51%)
eve	NP_523670.2	Homeobox	74..126	CDD:278475	26/51 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840