DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and otx5

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_851848.2	Gene:	otx5 / 353179	ZFINID:	ZDB-GENE-030508-1	Length:	289	Species:	Danio rerio

Alignment Length:	268	Identity:	83/268 - (30%)
Similarity:	111/268 - (41%)	Gaps:	84/268 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 RKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLR 533
            ||.:|.||:||..|:|.||..|.:|.|||:|.||.:|.||.|||:|:||||.|||||.|::::.:
Zfish    36 RKQRRERTTFTRAQLDVLEALFSKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQ 100

  Fly   534 NQRRT-------------------------------PNSTGASATSSSTSATASLTDSPNSLSAC 567
            ...:|                               |...|.:.|.||:|||.|:. ||.|:|..
Zfish   101 TSGQTKPRPPKKKSSPARDSSASEPSASTSGPYSPPPPPPGTAITPSSSSATVSIW-SPASISPL 164

  Fly   568 SSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESP-TPIPHIRPSCTSDNDNGRQS 631
            ...||    .||.:.:...|.|.|.|   .||..|....:|.|. |.:
Zfish   165 PDPLS----APSTACLQRSSYPMTYS---QAPAYGQSYAASSSYFTGL----------------- 205

  Fly   632 EDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFG---AMYSNMHHTALS 693
             ||....||.                 |.|..|...|:||.    ||:..   |..|:..:||.|
Zfish   206 -DCSSYLSPM-----------------HPQLSASGGALSPM----SGALSQSPASLSSQGYTAAS 248

  Fly   694 MSDSYGAV 701
            :  .:|.|
Zfish   249 L--GFGTV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
otx5	NP_851848.2	Homeobox	42..94	CDD:278475	32/51 (63%)
otx5	NP_851848.2	TF_Otx	157..231	CDD:281521	29/119 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910