Protein Alignment ey and EVX2

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001073927.1
• Gene: EVX2 / 344191
• HGNCID: 3507
• Length: 476
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 136/574 - (23%)
• Similarity: 198/574 - (34%)
• Gaps: 185/574 - (32%)

  Fly   281 LNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPL---VGQSP---------- 332
            |:|..:|...::...|...|:.|.|.  |:||.|...|..|  :|||   :|:.|
Human    16 LHSPTAGKRFSNLSNSAGNAVLEALE--NSQHPARLSPRLP--SAPLHSALGELPAKGKFEIDTL 76

  Fly   333 ---NHLGTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASG 394
               .|.|:.|:....:....::.::       |.|||     .:.:|..:||...: ..:|..|.
Human    77 FNLQHTGSESTVSSEISSAAESRKK-------PGHYS-----EAAAEADMSSDVEV-GCSALRSP 128

  Fly   395 PSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSG-----EGENSNGGASN 454
            ..|..:....|:.:..|..|                ...|..:..:|||     .|...:||::.
Human   129 GGLGAAQLKENNGKGYAESG----------------SAAGTTTSASGSGLGSLHGGSGGSGGSAA 177

  Fly   455 IGNTED--DQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQV 517
            :|.:..  ||.|        |.||:||.:||..|||||.|.:|.....|..||..:.|||..|:|
Human   178 LGGSGSGADQVR--------RYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKV 234

  Fly   518 WFSNRRAKWRREEKLRNQRR-------TPNSTGASATSS---------------STSATASLTDS 560
            ||.|||.|.:|:....:...       |...|.|:||.|               ....||:
Human   235 WFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPFHSHVPLHYYPHVGVTAA---- 295

  Fly   561 PNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDN 625
              :.:|.:|..:.:|..|..::|..|.:...||.                    |:.||..
Human   296 --AAAAAASGAAAAASSPFATSIRPLDTFRALSH--------------------PYSRPEL---- 334

  Fly   626 DNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHT 690
                       :||           ..|       .|....||.:..||               :
Human   335 -----------LCS-----------FRH-------PGLYQAPAAAAGLN---------------S 355

  Fly   691 ALSMSDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHHHIV--- 752
            |.|.:.:..|.....|   ||....||||     |...|.|...||.:......|.|....:
Human   356 AASAAAAAAAAAAAAS---SAAAAGAPPS-----GGSAPCSCLSCHSSQSAAAAAAAAAAALGSR 412

  Fly   753 -----PGDGGRPAGVGLGSGQSANLGASC----SGSGY-----EVLSAYALPPP 792
                 .|.||...|.|.|:|..::.|.|.    |.||:     .|||..|:.||
Human   413 GGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYSAAVLSKTAVSPP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
		Homeobox	475..527	CDD:278475	27/51 (53%)
EVX2	NP_001073927.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		7/42 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..185		10/58 (17%)
		Homeobox	192..244	CDD:278475	27/51 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910