DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and nkx3-2

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_835233.1	Gene:	nkx3-2 / 337865	ZFINID:	ZDB-GENE-030127-1	Length:	245	Species:	Danio rerio

Alignment Length:	197	Identity:	49/197 - (24%)
Similarity:	84/197 - (42%)	Gaps:	47/197 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 QALQQHQQQSWPPRHYSGSWYPTSLSEIPI-------------SSAPNIASVTAYASGPSLAHSL 401
            ||:...:::|   ||         |:|:.:             ..||..:..|.:.:..| ...|
Zfish    14 QAILNRKEES---RH---------LNELDVCFSKSACWKIFDEMDAPERSDETEHKNYDS-DSGL 65

  Fly   402 SPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNI---GNTEDDQA 463
            |..||               |...|..|.|.|...:|||   :.|::..|.|:.   .||.::::
Zfish    66 SEDND---------------AKAQIDAKPEKDADLADET---DQESAAKGLSDCVSDCNTAEEKS 112

  Fly   464 RLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528
            ....|::.:|:|.:|::.|:..||:.|....|.....|..||..:.|.|.::::||.|||.|.:|
Zfish   113 GDAPKQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 177

  Fly   529 EE 530
            .:
Zfish   178 RQ 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
nkx3-2	NP_835233.1	COG5576	65..>177	CDD:227863	37/129 (29%)
nkx3-2	NP_835233.1	Homeobox	123..176	CDD:278475	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910