DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP005027

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_560610.5	Gene:	AgaP_AGAP005027 / 3292283	VectorBaseID:	AGAP005027	Length:	303	Species:	Anopheles gambiae

Alignment Length:	314	Identity:	59/314 - (18%)
Similarity:	100/314 - (31%)	Gaps:	92/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKI 180
            |..|::|:.....|.....||:||.:..|.|..|:..|.|...|..:..||..|::.|.|.:..|
Mosquito    25 DKDRRRIISAFEKGVSASAISKILNIKQGTVYGIIKNYKERLQIDSKKRGGQNPKLLTPEAIDSI 89

  Fly   181 SQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSI 245
            .::..|..|:....:.:|:.:::                             |...|||:....:
Mosquito    90 HRWVDENESVTLKVLTERVFKDH-----------------------------GLRVSSTTVAREV 125

  Fly   246 SA--------KVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGEGSEQEAIY 302
            .|        |:....          .|.||:..|:    ..|.:.....|.
Mosquito   126 RAYKNPTKMPKIQYRC----------DRCTLNHQTE----ECPFDDEVIEGL------------- 163

  Fly   303 EKLRLLNTQHAAG----PGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPPR 363
             |....|..|.|.    |...:|...:||..:...|              .::..|....:..|.
Mosquito   164 -KCSTCNEPHGANDSQCPTRKDPFATSPLPSEEIEH--------------EESSTQSSLDALSPL 213

  Fly   364 HYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAH-------SLSPPNDIESL 410
            ....|| |:|.::.| :...:|.:.|..:....::|       :||...|..||
Mosquito   214 KAEPSW-PSSATQSP-ARETSIVTATPLSFQNDVSHIIIEEADALSTSTDANSL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	23/104 (22%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475
AgaP_AGAP005027	XP_560610.5	HTH	28..111	CDD:304362	22/82 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910