DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP009630

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_553424.2	Gene:	AgaP_AGAP009630 / 3292016	VectorBaseID:	AGAP009630	Length:	410	Species:	Anopheles gambiae

Alignment Length:	260	Identity:	52/260 - (20%)
Similarity:	90/260 - (34%)	Gaps:	66/260 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 PARAAP--LVG--------------QSPNHLGTRSSHPQLVHGNHQALQQHQQQSWPP------- 362
            |.|..|  :||              ||....|.....|:.|....:..:..|:.:.||
Mosquito     7 PGRTTPETMVGGIRKWEQLSRTAGKQSLAPFGDGYETPRQVKSRKEDSESDQEPTEPPEEDDQYT 71

  Fly   363 -RHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDI 426
             :|||.|.:.|...|.....|.......:..:.|.:..|..||...|..:.:.|..
Mosquito    72 EQHYSESEFHTEQEEDDDEQADRNEHGWSEHAHPPIQVSQYPPKRFEQGSHLLHID--------- 127

  Fly   427 HLKKELDGHQSDETGSGEGENSNG----GASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLE 487
            .:..||...:...:|...|....|    ||:...:....|       :.|::..||:.:::
Mosquito   128 FITDELGRFELPSSGQSRGRRPMGMVGSGATGRKSASGQQ-------QSQQHNISFSRERV---- 181

  Fly   488 KEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTS 552
            :|.|||:       :.|..:|......:|...|::..|           ||.::..:.|||::|:
Mosquito   182 REIERTN-------QILLRRIITTRPTLQTQTSSKPVK-----------RTSSTNASPATSAATN 228

Fly 553 552
Mosquito 229 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	11/51 (22%)
AgaP_AGAP009630	XP_553424.2	KIAA1430	<173..246	CDD:290590	17/78 (22%)
		PDZ	250..319	CDD:238080
		PDZ	335..399	CDD:238080
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900