DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and AgaP_AGAP005346

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_555988.2	Gene:	AgaP_AGAP005346 / 3289950	VectorBaseID:	AGAP005346	Length:	461	Species:	Anopheles gambiae

Alignment Length:	477	Identity:	119/477 - (24%)
Similarity:	175/477 - (36%)	Gaps:	122/477 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 PNHLGTRSSHPQLVHGNHQALQQHQQQSWPPRH----YSGSWYPT----SLSEIP-ISSAPNIAS 387
            |:..||.|:...   |.::.:......|:|..|    ::...|.|    |.|.:. :....|..|
Mosquito    37 PDRSGTASTSSA---GCYRGMDDRLASSYPIAHPAQLHNSMVYQTLMTRSASAVEFLDVNKNETS 98

  Fly   388 VTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGA 452
            ...:|:.       .||:  |...|...:.:|...|.|          ...|..| ||..|.|.|
Mosquito    99 AVPFAAD-------RPPS--ERAESSSPESSCNEDTMD----------NCSEIAS-EGSASGGLA 143

  Fly   453 SNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQV 517
            ::     ||:.:        |.||:|:..||.:||.||||..|..|..|..||.::.|.|.:|::
Mosquito   144 AH-----DDRKK--------RPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLHLTETQIKI 195

  Fly   518 WFSNRRAKWRRE-----EKLRNQRRTPNSTGASATSSSTSATASL-TDSPNSLSACSSLL----- 571
            ||.|||.||:|:     |.|.:...:....|:.|..........| :.:||..:...|||
Mosquito   196 WFQNRRTKWKRKYTADVESLASHYYSQLGIGSFARPMVVGDRLWLFSQTPNGPTPVQSLLLNGPQ 260

  Fly   572 SGSAGG--PSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPT--PIPHIRPSCTSDNDNGRQSE 632
            .|:||.  |::    |:..|:.:..   .|||...|..:..|.  |.|.:.|.....:
Mosquito   261 PGAAGASHPAL----GMQHPAAIRP---YPTLSGPIPMNAGPNFPPRPGMPPGAYLSS------- 311

  Fly   633 DCRRVCSPCPLGVGGHQNTHHIQS----NGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALS 693
                :.|....|.||.  .|.|.|    :..||.|.|.|.          |.|.:....::||..
Mosquito   312 ----IPSAAAAGPGGF--LHKIPSPSPQSRMAQPHGLRPL----------SSGELLEGAYYTAAG 360

  Fly   694 MSDSYGAVTPIPSFNHSAV---GPLAPPSPIPQQGDL-----TPSSLYPCHMTLRPPPMAPAHHH 750
            |        |.|.||.:.:   |.||.........||     .||::.....|..|...:.|
Mosquito   361 M--------PGPKFNPNELINGGLLATDGNSSGIADLERAFGNPSNMIESLATSNPTEASIA--- 414

  Fly   751 IVPGDGGRPAGVGLGSGQSANL 772
                     .||..|..:.|:|
Mosquito   415 ---------GGVRTGGKKGADL 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	25/51 (49%)
AgaP_AGAP005346	XP_555988.2	Homeobox	152..205	CDD:278475	25/52 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910