DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Hoxc5

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001101586.1	Gene:	Hoxc5 / 315341	RGDID:	1307584	Length:	222	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	64/262 - (24%)
Similarity:	92/262 - (35%)	Gaps:	85/262 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 NSGEGSEQEA---IYEKLRL---------LNTQH----AAGPGPLEPARAAPLVGQSPNHLGTRS 339
            |.|..||.:|   .|..|.|         .|:.|    ||.| ...|.|.|.....:|.|
  Rat    26 NYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANP-RAHPDRPACSAAAAPGH----- 84

  Fly   340 SHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPS-LAHSLSP 403
                       ||.:.:.....|..||......:|.|...||. .|....|....|: |:...:|
  Rat    85 -----------ALGRDEAAPLNPGMYSQKAARPALEERAKSSG-EIKEEQAQTGQPAGLSQPPAP 137

  Fly   404 PNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILK 468
            |            :..|..|: :|:..|.||
  Rat   138 P------------QIYPWMTK-LHMSHETDG---------------------------------- 155

  Fly   469 RKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLR 533
               :|:|||:|..|...|||||....|.....|..:|..:.|.|.:|::||.|||.||:::.|::
  Rat   156 ---KRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMK 217

  Fly   534 NQ 535
            ::
  Rat   218 SK 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
Hoxc5	NP_001101586.1	COG5373	65..>142	CDD:227665	22/106 (21%)
Hoxc5	NP_001101586.1	Homeobox	158..212	CDD:395001	23/53 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910