DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and dlx5a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571381.2	Gene:	dlx5a / 30569	ZFINID:	ZDB-GENE-990415-49	Length:	282	Species:	Danio rerio

Alignment Length:	291	Identity:	59/291 - (20%)
Similarity:	111/291 - (38%)	Gaps:	88/291 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 PTSLSEI--PISSAPNIASVTA-----YASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHL 428
            |..||.:  |...:|.:...||     |:....:.|....||.    .:.|
Zfish    20 PFQLSTMHHPSQESPTLPESTATDSGYYSPAGGVHHGYCSPNS----GTYG-------------- 66

  Fly   429 KKELDGHQSDETGSGEGENSNGGASNIG---------------------------------NTED 460
             |.|:.:|....|      .||.:.|..                                 .|.:
Zfish    67 -KPLNAYQYQYHG------VNGSSGNYSAKSYPDYGSYSTAYHQYAGTYNRVQSQPSPQEKETAE 124

  Fly   461 DQARLI--LKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRR 523
            .:.|::  ..:|:::.||.:::.|:.:|::.|:.|.|..:..|..||..:||.:.::::||.|:|
Zfish   125 PEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQNTQYLALPERAELAASLGLTQTQVKIWFQNKR 189

  Fly   524 AKWRREEKLRN----QRRTPNSTGASATSSSTSATASLTDSP--------NSLSACSSLLSGSAG 576
            :|.::  .::|    ...:|:|:...|.:|..|.....:..|        |..:|.|:.|..::.
Zfish   190 SKLKK--IMKNGELPPEHSPSSSDPMACNSPQSPAVWDSQGPQRPHHQPQNINTAASTFLESASS 252

  Fly   577 G--PSVSTING-LSSPSTLSTNVNAPTLGAG 604
            .  .|...:|. |.:|.||    ::..||:|
Zfish   253 SWYSSTGAMNSHLQAPGTL----HSLALGSG 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	17/51 (33%)
dlx5a	NP_571381.2	DLL_N	31..118	CDD:289198	15/111 (14%)
dlx5a	NP_571381.2	Homeobox	140..193	CDD:278475	17/52 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910