Protein Alignment ey and pax6a

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_009296153.1
• Gene: pax6a / 30567
• ZFINID: ZDB-GENE-990415-200
• Length: 459
• Species: Danio rerio
• Alignment Length: 595
• Identity: 254/595 - (42%)
• Similarity: 295/595 - (49%)
• Gaps: 203/595 - (34%)

  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQ--------------VSNGC 145
            :|.||||||||||||.||||||||||||||||||||||||||||||              |||||
Zfish    29 NEGHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGC 93

  Fly   146 VSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNI 210
            ||||||||||||||||||||||||||||.|||.||:|||||||||||||||||||.|.|||||||
Zfish    94 VSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNI 158

  Fly   211 PSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLM 275
            ||||||||||||||::|:|.
Zfish   159 PSVSSINRVLRNLASEKQQM--------------------------------------------- 178

  Fly   276 QTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSS 340
                        ||         :.:|||||:||                   ||:    ||..:
Zfish   179 ------------GA---------DGMYEKLRMLN-------------------GQT----GTWGT 199

  Fly   341 HPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPN 405
            .|                         .|||.       :|.|                  ..||
Zfish   200 RP-------------------------GWYPG-------TSVP------------------GQPN 214

  Fly   406 DIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRK 470
                      |..|               .|||    |.|||:|..:||..::::.|.||.||||
Zfish   215 ----------QDGC---------------QQSD----GGGENTNSISSNGEDSDETQMRLQLKRK 250

  Fly   471 LQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQ 535
            |||||||||.:||::||||||||||||||||||||.||.||||||||||||||||||||||||||
Zfish   251 LQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQ 315

  Fly   536 RRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSS-----PSTLSTN 595
            ||..:::.:....||:.:|:.....|...:.. |..|||..|.|.:.:....|     ||....|
Zfish   316 RRQASNSSSHIPISSSFSTSVYQPIPQPTTPV-SFTSGSMLGRSDTALTNTYSALPPMPSFTMAN 379

  Fly   596 VNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHA 660
             |.|...:...|.....|        ||.:.|||..:      :..|..:..|.|:..:.::|..
Zfish   380 -NLPMQPSQTSSYSCMLP--------TSPSVNGRSYD------TYTPPHMQAHMNSQSMAASGTT 429

  Fly   661 QGHALVPAIS 670
            ....:.|.:|
Zfish   430 STGLISPGVS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	116/136 (85%)
		Homeodomain	473..528	CDD:459649	48/54 (89%)
pax6a	XP_009296153.1	PAX	31..169	CDD:128645	116/137 (85%)
		Homeodomain	253..308	CDD:459649	48/54 (89%)