DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and dlx4a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571375.1	Gene:	dlx4a / 30561	ZFINID:	ZDB-GENE-980526-73	Length:	250	Species:	Danio rerio

Alignment Length:	279	Identity:	67/279 - (24%)
Similarity:	115/279 - (41%)	Gaps:	70/279 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   337 TRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPT------SLSEIPISSAPNIASVTAYASGP 395
            ::|:..:..||    .|.|||.|....|   :.||.      :.|:...:.:|..||.    |.|
Zfish    16 SKSAFLEFSHG----YQSHQQHSPGVSH---AHYPVHGLHQGAHSQYDAAFSPGAASY----SRP 69

  Fly   396 SLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTED 460
             ||:..|..:.... |.:.:|.|..|            |:...|....|.::|         .|.
Zfish    70 -LAYHYSTAHHHPG-AYLPYQHNSAV------------GYSRVEDADSEKQSS---------IES 111

  Fly   461 DQARLILK-RKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRA 524
            .:.||..| :|:::.||.:::.|:.:|.:.|::|.|..:..|..||.|:||.:.::::||.|:|:
Zfish   112 GEIRLNGKGKKIRKPRTIYSSLQLQALNQRFQQTQYLALPERADLAAKLGLTQTQVKIWFQNKRS 176

  Fly   525 KWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSP 589
            |:::..|          .|:|.........||.:.:|     ||         |.:..:..:|.|
Zfish   177 KYKKIMK----------HGSSGPEGEHLQAASASGAP-----CS---------PGMPPLWDVSMP 217

  Fly   590 STLSTNVNAPTLGAGIDSS 608
            |.     .||....|..:|
Zfish   218 SK-----GAPIHSGGYMNS 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
dlx4a	NP_571375.1	COG5576	98..206	CDD:227863	34/140 (24%)
		Homeobox	126..179	CDD:278475	18/52 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..202		5/29 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910