Protein Alignment ey and pax3a

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 751
• Identity: 211/751 - (28%)
• Similarity: 280/751 - (37%)
• Gaps: 295/751 - (39%)

  Fly   101 VNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 165
            ||||||||:.|||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||||.|||
Zfish    38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIG 102

  Fly   166 GSKPRVATA-EVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQ 229
            ||||:.:|. :|..||.:||||.|.:|:|||||:||::.:|..:|:||||||:|:||
Zfish   103 GSKPKQSTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLR-------- 159

  Fly   230 QSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNSGE 294
                                 ...|||                                    |:
Zfish   160 ---------------------CKFGGN------------------------------------GD 167

  Fly   295 GSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNH-----LGTRSSHPQLVHGNHQALQQ 354
            ..|.:...||..:...:..|                  .|     ||.||||
Zfish   168 EDEDDDEVEKREIEENERRA------------------KHSIDGILGDRSSH------------- 201

  Fly   355 HQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNC 419
                                                                             
Zfish   202 ----------------------------------------------------------------- 201

  Fly   420 PVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQID 484
                             |||                |:..|.:..|.||||.:|:||:||.:|::
Zfish   202 -----------------SDE----------------GSDVDSEPGLPLKRKQRRSRTTFTAEQLE 233

  Fly   485 SLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNST---GASA 546
            .||:.||||||||::.||.||.:..|.|||:|||||||||:||::.. .||....|..   |...
Zfish   234 ELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG-ANQLMAFNHLIPGGFPP 297

  Fly   547 TSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESP 611
            ::.|:.....|.|||...|             |:|.::  ..|||:                ..|
Zfish   298 SAMSSLQPYQLADSPYPPS-------------SISQVS--EQPSTV----------------HRP 331

  Fly   612 TPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFN 676
            .|:|.     ||.:.:|              ||.|          .|..:|.:.....|.|..|:
Zfish   332 QPLPP-----TSVHQSG--------------LGSG----------PGAQEGSSAYCLSSGRHGFS 367

  Fly   677 SGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPI---PQQGDLTPSSLYP--CH 736
            ..|.|.:.:..|...::.|.|.|..:.:....:....|..|.|..   |..|.|.||:..|  ||
Zfish   368 GYSDGYVAAPGHANPVNPSISNGLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPSTGMPASCH 432

  Fly   737 MTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAAD 801
            .:.|        ...:||....||   |.|.|| ...:|.|..||.|             ...|.
Zfish   433 SSQR--------LEALPGLPSMPA---LPSSQS-YCPSSYSSPGYSV-------------DHVAS 472

  Fly   802 SSFSAASSASANVTPHHTIAQESCPSPCSSASHFGV 837
            ..:|....:..|.:...|:.:.|...|...|| ||:
Zfish   473 YQYSQYGQSKVNTSTVTTVERLSRVYPLKRAS-FGL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	79/120 (66%)
		Homeobox	475..527	CDD:278475	32/51 (63%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	79/120 (66%)
		Homeobox	223..276	CDD:278475	32/52 (62%)
		Pax7	350..394	CDD:289156	10/43 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810