Protein Alignment ey and pax2a

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_021336168.1
• Gene: pax2a / 30425
• ZFINID: ZDB-GENE-990415-8
• Length: 519
• Species: Danio rerio
• Alignment Length: 692
• Identity: 201/692 - (29%)
• Similarity: 282/692 - (40%)
• Gaps: 229/692 - (33%)

  Fly    98 HSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILG-------RYYE 155
            |.||||||||||.||||||..||:||||||.|.|||||||.|:||:||||||||       ||||
Zfish    20 HGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGSYQKDLIRYYE 84

  Fly   156 TGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPSVSSINRVL 220
            ||||:|..||||||:|||.:||.||::|||:.|::||||||||||.|.||.||.:||||||||::
Zfish    85 TGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRII 149

  Fly   221 RNLAAQK-EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSS 284
            |....|. ...|.|:|:..::||::|         |::.:.....  |.|.:..:..||:|..||
Zfish   150 RTKVQQPFHPSSDGTGTPLSTAGHTI---------GDLESTPYTL--TYSCALSVPSTASPPVSS 203

  Fly   285 ESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNH 349
                |||...||     |....:|....:.|.                    .|.....|..|||
Zfish   204 ----ASNDPVGS-----YSINGILGIPRSNGE--------------------KRKRDDVLWSGNH 239

  Fly   350 QALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIG 414
                                                                             
Zfish   240 ----------------------------------------------------------------- 239

  Fly   415 HQRNCPVATEDIHLKKELDGHQSDETGS-GEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSF 478
                             |||.:....|| |.|.||:    :.|:.|.      |::.|:.:  :|
Zfish   240 -----------------LDGRKIGYYGSDGSGPNSD----SQGSVES------LRKHLRAD--AF 275

  Fly   479 TNDQIDSLEKEFERTHYPDVF-----ARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRT 538
            |..|:::|::.|||..|||||     .:...|.:..||..               ...|...:.:
Zfish   276 TQQQLEALDRVFERPSYPDVFPTSEHIKPEQANEYSLPAL---------------NPGLDEVKPS 325

  Fly   539 PNSTGASATSSSTSATASLTDSPNSLSAC-------SSLLSGSAGGPSVSTINGLS-----SPST 591
            .:::.:|...||.|.:..:....:|.|.|       :||...:   ||...::||:     .||
Zfish   326 LSTSVSSDLGSSVSQSYPVVTESHSSSMCVKQEPHEASLAPFT---PSSLAVSGLAELLPLQPS- 386

  Fly   592 LSTNVNAPTLGAGIDSSESPTPIPHIRPS-CTSDNDN---GRQSEDCRRVCSP---CPLGVGGHQ 649
            :|.:.:.|..||          ..|..|| |...:.:   ||:.........|   .|.|.|.:.
Zfish   387 VSVDASTPCYGA----------YAHHAPSYCQYTSQHIIAGREMASTTLPGYPPHVPPTGQGSYP 441

  Fly   650 NTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGP 714
            .             :.:..:.|..:|:    |..||:..:|  :.::::....|.....|.. .|
Zfish   442 T-------------STLAGMVPGSDFS----GNPYSHPQYT--TYNEAWRFSNPALLMPHPG-AP 486

  Fly   715 LAPPSPIPQQGDLTPSSLYPCHMTLRPPPMAPAHH---HIVP 753
            ..|..|:|    :|.:|.:      |.|.....|.   ||||
Zfish   487 GLPLLPLP----MTATSYH------RSPVKLQDHGRGLHIVP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	93/129 (72%)
		Homeobox	475..527	CDD:278475	15/56 (27%)
pax2a	XP_021336168.1	PAX	19..150	CDD:128645	93/129 (72%)
		Pax2_C	391..500	CDD:315141	26/142 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910