DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and dbx1a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571233.1	Gene:	dbx1a / 30394	ZFINID:	ZDB-GENE-000128-8	Length:	314	Species:	Danio rerio

Alignment Length:	373	Identity:	75/373 - (20%)
Similarity:	127/373 - (34%)	Gaps:	138/373 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 SSTDLMQTATPLNSSESGGASNSGEGSEQEAIYEKLRLLN-------TQHAAGPGPLEPARAAPL 327
            |.|.....|:|.||:..             :|.:..|:|:       .:|    ||..|  ..|:
Zfish    49 SQTAHSPCASPPNSTPL-------------SIPDNCRILDRVSPGITEKH----GPCSP--KTPV 94

  Fly   328 VGQSPNHL-----------GTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISS 381
            ..:.|.:|           ..:::.|..||..|            |:.:|..::..|.
Zfish    95 SSKDPTYLKFGVSAILAPSPKKATSPPSVHSIH------------PKGFSVPYFDGSF------- 140

  Fly   382 APNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGE 446
            .|.:.|  :|...||            |:..|....:.|:|                    ..|:
Zfish   141 CPFVRS--SYFPAPS------------SVVPIPGTFSWPLA--------------------ARGK 171

  Fly   447 NSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHY---PDVFARERLAGKI 508
            ...|               :|:|.:      |::.|..:|||.|::..|   ||   |::||.|:
Zfish   172 PRRG---------------MLRRAV------FSDVQRKALEKMFQKQKYISKPD---RKKLAAKL 212

  Fly   509 GLPEARIQVWFSNRRAKWR--REEKLRN-----QRRTPNSTGASATSSSTSATASLTDSPNSLSA 566
            ||.::::::||.|||.|||  :|.:|.:     ::..|..|......|.....:|..:..:...|
Zfish   213 GLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKTNPHPDLSDVGKKSSEDEDEDDACA 277

  Fly   567 CSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPI 614
            .|...              ||....:|.:.::.......|.|||...|
Zfish   278 PSHFC--------------LSPRRVMSNSTDSSITFKHSDFSESEDEI 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/54 (39%)
dbx1a	NP_571233.1	Homeobox	178..231	CDD:278475	22/61 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..279		7/44 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..314		5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910