DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and en2a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571119.2	Gene:	en2a / 30243	ZFINID:	ZDB-GENE-980526-167	Length:	265	Species:	Danio rerio

Alignment Length:	210	Identity:	56/210 - (26%)
Similarity:	81/210 - (38%)	Gaps:	60/210 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   348 NHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIES--- 409
            ||.|.:.| ..:.|.....||..|.           ..||.|..:||...|       :|||
Zfish    67 NHGARENH-NPTGPSTGQVGSTVPA-----------EEASTTHTSSGGKEA-------EIESEEP 112

  Fly   410 LASIGHQRNCPVATEDIHLKKELDGHQSD---ETGSG-----------------EGENSNGGASN 454
            |...|.       ..|..|..|.|..||:   :||.|                 .|..|......
Zfish   113 LKPRGE-------NVDQCLGSESDSSQSNSNGQTGQGMLWPAWVYCTRYSDRPSSGPRSRKPKKK 170

  Fly   455 IGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWF 519
            ..:.||           :|.||:||.:|:..|:.||:...|.....|:.||.::||.|::|::||
Zfish   171 AASKED-----------KRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWF 224

  Fly   520 SNRRAKWRREEKLRN 534
            .|:|||.::...::|
Zfish   225 QNKRAKIKKASGVKN 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
en2a	NP_571119.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..142		27/100 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..180		5/35 (14%)
		Homeobox	179..232	CDD:278475	22/52 (42%)
		Engrail_1_C_sig	234..263	CDD:287495	1/6 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910