DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and mixl1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_571015.3	Gene:	mixl1 / 30115	ZFINID:	ZDB-GENE-000208-20	Length:	327	Species:	Danio rerio

Alignment Length:	308	Identity:	84/308 - (27%)
Similarity:	115/308 - (37%)	Gaps:	101/308 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   456 GNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFS 520
            |.:..|...|...|   |.||:||..|||.|||.:..|.|||::.||:|....||||:||||||.
Zfish    46 GASRADNVSLFTHR---RKRTNFTQQQIDVLEKVYLDTKYPDIYLREKLEALTGLPESRIQVWFQ 107

  Fly   521 NRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTING 585
            |||||.||:..:    ..||.|..:..            :||:|     |:.......:.|.:..
Zfish   108 NRRAKSRRQVGI----SIPNKTSGNIL------------TPNNL-----LMHQFTTHQNHSGLEN 151

  Fly   586 LSSPSTLSTNVNAPTLGAGIDSSE-----------SPTPIPHIRPSCTSDNDNGRQSEDCRRVCS 639
            |...||.:.:.....|   |:|||           .||.||.:. |.|.:|
Zfish   152 LQRTSTFTADSFHQQL---INSSEEKISTIKGDIYDPTTIPCMF-SRTQEN-------------- 198

  Fly   640 PCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFGAMYSNMH--------HTALSMSD 696
              |:      .|.|:.            .:.||      |:...|...|        |...:|..
Zfish   199 --PI------KTDHLS------------VVVPR------SYTQQYPKEHEQFTHSANHAKSTMKQ 237

  Fly   697 ---SYGAVTPIPSFNHSAVGP----LAPPSPIPQQGDLTPSSLYPCHM 737
               .|....|     :..:||    :.|  |:|.|.:...||..|.|:
Zfish   238 FLVEYDNFPP-----NKTIGPEMKVVIP--PLPSQSNFMMSSSSPKHI 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	32/51 (63%)
mixl1	NP_571015.3	Homeobox	61..114	CDD:278475	32/52 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810