DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Gm4981

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001030041.1	Gene:	Gm4981 / 245263	MGIID:	3645498	Length:	291	Species:	Mus musculus

Alignment Length:	221	Identity:	58/221 - (26%)
Similarity:	88/221 - (39%)	Gaps:	24/221 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   467 LKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEK 531
            ::...:|..|..|..|...|.:.|||...|....||.||.:.||||..|..|..|:||:
Mouse     1 MRSSSRRPHTGLTLSQRRILAQAFERNPRPGCATREELALETGLPEDMIHTWLKNKRAR------ 59

  Fly   532 LRNQRRTPNSTGASATSSSTS--ATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPS---- 590
             |::|..|.:......:|..|  |.|......:.::..|||....||...:.|.:...|||
Mouse    60 -RHRRGRPTAQDQDLLASQVSGGAPAGPVGRGHEVAQESSLPQEEAGSTGMDTTSTSYSPSFCRE 123

  Fly   591 TLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLG--------VGG 647
            :..:.|:.|. |||  ..|.||...::.|.....::...:.:....|..|..||        .|.
Mouse   124 SQLSQVSQPR-GAG--QKEVPTQAGNVGPLELLLDELQDEVQVKEHVPDPLDLGSDPGAREPEGS 185

  Fly   648 HQNTHHIQSNGHAQGHALVPAISPRL 673
            ..:...:....::..|..||:||..|
Mouse   186 QDSLQSLDEAANSGWHTSVPSISSTL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
Gm4981	NP_001030041.1	homeodomain	6..56	CDD:238039	19/49 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900