Protein Alignment ey and Shox2

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_038693.1
• Gene: Shox2 / 20429
• MGIID: 1201673
• Length: 331
• Species: Mus musculus
• Alignment Length: 418
• Identity: 89/418 - (21%)
• Similarity: 134/418 - (32%)
• Gaps: 218/418 - (52%)

  Fly   441 GSGEGENSNGGAS-----NIGNTE---------------------------DDQARLILKRKLQR 473
            |.|.|..:.||.|     ::|..|                           :|:.:..:|::  |
Mouse    80 GGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKDDAKGMEDEGQTKIKQR--R 142

  Fly   474 NRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRT 538
            :||:||.:|::.||:.|:.|||||.|.||.|:.::||.|||:||||.|||||.|::|
Mouse   143 SRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQE-------- 199

  Fly   539 PNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGA 603
                                   |.|.  ..:|.|:|.
Mouse   200 -----------------------NQLH--KGVLIGAAS--------------------------- 212

  Fly   604 GIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPA 668
                                      |.|.||
Mouse   213 --------------------------QFEACR--------------------------------- 218

  Fly   669 ISPRLNFNSGSFGAMYSNMHHTALSM---SDSYGAVTPIPSFNHSAVGPLAPPSPIPQQGDLTPS 730
            ::|.:|..              ||.|   .||:..|||: ||.              .|..|...
Mouse   219 VAPYVNVG--------------ALRMPFQQDSHCNVTPL-SFQ--------------VQAQLQLD 254

  Fly   731 SLYPCHMTLRPPPMAPAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSA--YALPPPP 793
            |           .:|.||||:.|                 :|.|.   :.|.:..|  :.||...
Mouse   255 S-----------AVAHAHHHLHP-----------------HLAAH---APYMMFPAPPFGLPLAT 288

  Fly   794 MASSSAADSSFSAASSASANVTPHHTIA 821
            :|:.||:.:|..||::|:...:.:.:||
Mouse   289 LAADSASAASVVAAAAAAKTTSKNSSIA 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
		Homeobox	475..527	CDD:278475	31/51 (61%)
Shox2	NP_038693.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..140		9/59 (15%)
		Homeobox	143..197	CDD:395001	31/53 (58%)
		OAR	311..327	CDD:397759	2/6 (33%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	313..326		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940