DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and ceh-30

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_508524.2	Gene:	ceh-30 / 191620	WormBaseID:	WBGene00000451	Length:	237	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	60/232 - (25%)
Similarity:	91/232 - (39%)	Gaps:	47/232 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   398 AHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEG---------ENSNGGAS 453
            |.|.||.|.|.|.:|..       .::.:........|.:|...|.:.         ..|:.|..
Worm    27 AASTSPCNKISSSSSFR-------ISDILEQSPNNSSHSNDHDPSPQSIKSDFSTSPRASSPGGD 84

  Fly   454 NIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVW 518
            .:|:...       .:|.::.||.||:.|:..||..||:..|..|..|..||.::||.:.:::.|
Worm    85 RMGSPGS-------CKKSRKARTIFTDKQLQELENTFEKQKYLSVQDRMDLAHRMGLTDTQVKTW 142

  Fly   519 FSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTI 583
            :.|||.||:|:                |||.     ..|...|.:|||..:|:..|....:..|.
Worm   143 YQNRRTKWKRQ----------------ATSG-----MDLLSEPGNLSAVQNLIRSSPYWANYITA 186

  Fly   584 --NGLSSPST-LSTNVNAPTLGAGIDSSESPTPIPHI 617
              .|...|.. |..::..|...|...||.|.:|..||
Worm   187 LPMGTQLPMMGLPMSMIVPPAHAFQPSSSSNSPSTHI 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
ceh-30	NP_508524.2	Homeobox	99..151	CDD:278475	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910