DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and ceh-1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_508796.2	Gene:	ceh-1 / 191614	WormBaseID:	WBGene00000428	Length:	171	Species:	Caenorhabditis elegans

Alignment Length:	175	Identity:	54/175 - (30%)
Similarity:	90/175 - (51%)	Gaps:	22/175 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 EDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEK 488
            ||:..::|.|.: ||| .:.:...::||.|:            .|.|::|.||:||.:|:.:||.
Worm     7 EDLLSEREKDSN-SDE-ATHQKSPADGGKSS------------RKLKMRRARTAFTYEQLVALEN 57

  Fly   489 EFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSA 553
            :|:.:.|..|..|..||.::.|.|.::::||.|||.||::    .|..:..|:.....:|..|..
Worm    58 KFKTSRYLSVVERLNLAIQLQLSETQVKIWFQNRRTKWKK----HNPGQDANTPQTPPSSDETQI 118

  Fly   554 TASLTDSPNSLSACSSLLSGSAGGPSVSTI-NGLSSPSTLSTNVN 597
            ...|..:|  :::.||||......|:.|.: .|.|.|.|| .|:|
Worm   119 QPILPANP--ITSFSSLLLPPIISPANSAVLQGTSIPLTL-FNLN 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	21/51 (41%)
ceh-1	NP_508796.2	COG5576	2..118	CDD:227863	39/128 (30%)
ceh-1	NP_508796.2	Homeobox	44..96	CDD:278475	21/51 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910