DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and Pou4f3

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_620395.2	Gene:	Pou4f3 / 18998	MGIID:	102523	Length:	338	Species:	Mus musculus

Alignment Length:	309	Identity:	65/309 - (21%)
Similarity:	96/309 - (31%)	Gaps:	99/309 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 GSEQEAIYEKLRLLNTQHAAGPG---PLEP------ARAAPLVGQSP----NHLGTRSSHPQLVH 346
            ||..|::..:...|........|   |.:|      ..:.|....||    :|....:|||.  |
Mouse    47 GSFDESLLARAEALAAVDIVSHGKNHPFKPDATYHTMSSVPCTSTSPTVPISHPAALTSHPH--H 109

  Fly   347 GNHQALQ----QHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAY---ASGPSLAHSLSP- 403
            ..||.|:    :|..   |....||...|.. |.:|....|:......:   |.|.|..|:::|
Mouse   110 AVHQGLEGDLLEHIS---PTLSVSGLGAPEH-SVMPAQIHPHHLGAMGHLHQAMGMSHPHAVAPH 170

  Fly   404 -------------PNDIESLASIGHQRNCPVATED------------------------------ 425
                         |.::|:.|....||...:....
Mouse   171 SAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLT 235

  Fly   426 ------IHLKKELDGHQSDETGSGEGENS-----NGGASNIGNTEDDQARLILKRKLQRNRTSFT 479
                  |.||..|.....:...:...:||     ||.                :||  |.|||..
Mouse   236 LSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGS----------------ERK--RKRTSIA 282

  Fly   480 NDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528
            ..:..|||..|.....|.......:|.|:.|.:..::|||.|:|.|.:|
Mouse   283 APEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	17/51 (33%)
Pou4f3	NP_620395.2	POU-IV box	56..65		1/8 (13%)
		POU	179..256	CDD:197673	9/76 (12%)
		Homeobox	277..331	CDD:395001	17/53 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910