DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and ceh-27

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001256348.1	Gene:	ceh-27 / 185853	WormBaseID:	WBGene00000449	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	55/226 - (24%)
Similarity:	94/226 - (41%)	Gaps:	38/226 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 PT--SLSEIPISSAPNIASVTAYASGPS-LAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKEL 432
            ||  :.|.:.||:....|:..:|.:.|: ..|..|..|...:.|:..:    |:||.     .:|
Worm    18 PTTDAFSTLSISAPATTAAQMSYFAFPNQYPHDFSSYNTSAAYATAPY----PMATH-----PQL 73

  Fly   433 DGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLEKEFERTHYPD 497
            ......:|..          .|:|.|  .|..:::.|:  :.|..|:..|:..||::|:...|..
Worm    74 ANFNRFQTNQ----------LNLGLT--TQQNMMISRR--KRRVLFSPQQVHVLERKFQINRYLS 124

  Fly   498 VFARERLAGKIGLPEARIQVWFSNRRAKWRREEK--------LRNQRRTPNS----TGASATSSS 550
            ...||.||..|.|...::::||.|:|.|.:|:||        .|:..|..:|    ..:.:..||
Worm   125 AADRENLAKSINLSATQVKIWFQNQRYKCKRQEKEKKMDGGCYRDSDRDTDSDRDNDSSGSLGSS 189

  Fly   551 TSATASLTDSPNSLSACSSLLSGSAGGPSVS 581
            .|......|........|::.|.:|..|.:|
Worm   190 MSGIKKEEDEDRKPFMPSAVSSDTACLPDIS 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	18/51 (35%)
ceh-27	NP_001256348.1	homeodomain	99..157	CDD:238039	19/59 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910