Protein Alignment ey and Pax7

DIOPT Version :10

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: XP_006538692.1
• Gene: Pax7 / 18509
• MGIID: 97491
• Length: 505
• Species: Mus musculus
• Alignment Length: 783
• Identity: 208/783 - (26%)
• Similarity: 269/783 - (34%)
• Gaps: 347/783 - (44%)

  Fly   101 VNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIG 165
            ||||||||:.|||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||||.|||
Mouse    38 VNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIG 102

  Fly   166 GSKPR-VATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNIPS--VSSINRVLRNLAAQK 227
            ||||| |||.:|..||.:||||.|.:|:||||||||::..|....:||  ||||:||||....:|
Mouse   103 GSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKK 167

  Fly   228 EQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESGGASNS 292
            |...
Mouse   168 EDDE------------------------------------------------------------- 171

  Fly   293 GEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVHGNHQALQQHQQ 357
             ||.::|...||
Mouse   172 -EGDKKEEDGEK----------------------------------------------------- 182

  Fly   358 QSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVA 422
                                                                             
Mouse   183 ----------------------------------------------------------------- 182

  Fly   423 TEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRKLQRNRTSFTNDQIDSLE 487
                ..|..:||...|:          |...:.|:..:.:..|.||||.:|:||:||.:|::.||
Mouse   183 ----KAKHSIDGILGDK----------GNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELE 233

  Fly   488 KEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTS 552
            |.||||||||::.||.||.:..|.|||:|||||||||:||::            .||
Mouse   234 KAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ------------AGA-------- 278

  Fly   553 ATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIP-H 616
                     |.|:|.:.||.|  |.|          |:.:      |||        .|..:| .
Mouse   279 ---------NQLAAFNHLLPG--GFP----------PTGM------PTL--------PPYQLPDS 308

  Fly   617 IRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHAQGHALVPAISPRLNFNSGSFG 681
            ..|:.|...|.|      ..|..|.||                           |....:.|...
Mouse   309 TYPTTTISQDGG------STVHRPQPL---------------------------PPSTMHQGGLA 340

  Fly   682 AMYSNMHHTALSMSDSYGAVTPIPSFNHSAVGPLAPPSPI-PQQGDLTPSSLYPCHMTLRPPPMA 745
            |..:     |...|.:|||.....|::.|.:.|.||.:.: |....|:|..:.........||..
Mouse   341 AAAA-----AADTSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPSAVPPQP 400

  Fly   746 PAHHHIVPGDGGRPAGVGLGSGQSANLGASCSGSGYEVLSAYALPPPPMASSSAADSSFSAASSA 810
            .|...|.|..|      ||.|..|  :.||||.....:....:||
Mouse   401 QADFSISPLHG------GLDSASS--ISASCSQRADSIKPGDSLP-------------------- 437

  Fly   811 SANVTPHHTIAQESCPSPCSSASHFGVAHSSGFSSDPISPAVSSYAHMSYNYASSANTMTPSSAS 875
                     .:|..||...|         ::|:|.||::         .|.|:....|.....|.
Mouse   438 ---------TSQSYCPPTYS---------TTGYSVDPVA---------GYQYSQYGQTAVDYLAK 475

  Fly   876 GTS 878
            ..|
Mouse   476 NVS 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	83/122 (68%)
		Homeodomain	473..528	CDD:459649	35/54 (65%)
Pax7	XP_006538692.1	PAX	34..161	CDD:128645	83/122 (68%)
		Homeodomain	218..274	CDD:459649	35/55 (64%)
		Pax7	347..385	CDD:403540	11/37 (30%)